MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae.
Calorie restriction (CR) robustly extends the lifespan of numerous species. In the yeast Saccharomyces cerevisiae, CR has been proposed to extend lifespan by boosting the activity of sirtuin deacetylases, thereby suppressing the formation of toxic repetitive ribosomal DNA (rDNA) circles. An alternat...
Guardado en:
Autores principales: | Oliver Medvedik, Dudley W Lamming, Keyman D Kim, David A Sinclair |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2007
|
Materias: | |
Acceso en línea: | https://doaj.org/article/93989e7a876647aabaa90ca605f5e9bd |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Msn2/4 transcription factors positively regulate expression of Atg39 ER-phagy receptor
por: Tomoaki Mizuno, et al.
Publicado: (2021) -
HIGH SPEED CENTRIFUGAL COUNTERCURRENT CHROMATOGRAPHY (HSCCC) ISOLATION AND IDENTIFICATION BY LC-MSn ANALYSIS OF THE POLAR PHENOLICS FROM VASCONCELLEA QUERCIFOLIA
por: QUISPE,CRISTINA, et al.
Publicado: (2013) -
Treatment response in dogs with naturally occurring grade 3 elbow osteoarthritis following intra-articular injection of 117mSn (tin) colloid.
por: John Donecker, et al.
Publicado: (2021) -
Yeast Cip1 is activated by environmental stress to inhibit Cdk1–G1 cyclins via Mcm1 and Msn2/4
por: Ya-Lan Chang, et al.
Publicado: (2017) -
Lifespan extension by methionine restriction requires autophagy-dependent vacuolar acidification.
por: Christoph Ruckenstuhl, et al.
Publicado: (2014)