ODE constrained mixture modelling: a method for unraveling subpopulation structures and dynamics.

Functional cell-to-cell variability is ubiquitous in multicellular organisms as well as bacterial populations. Even genetically identical cells of the same cell type can respond differently to identical stimuli. Methods have been developed to analyse heterogeneous populations, e.g., mixture models a...

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Autores principales: Jan Hasenauer, Christine Hasenauer, Tim Hucho, Fabian J Theis
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/939b3d72246243999e4f49303f11881e
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