A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons

Single nuclei RNA-seq has been used to characterize transcriptional signature of environment-related activity in cells of the dentate gyrus. Here the authors use this approach to show that whether a neuron will be reactivated in response to re-exposure to a previous environment can be predicted by i...

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Autores principales:	Baptiste N. Jaeger, Sara B. Linker, Sarah L. Parylak, Jerika J. Barron, Iryna S. Gallina, Christian D. Saavedra, Conor Fitzpatrick, Christina K. Lim, Simon T. Schafer, Benjamin Lacar, Sebastian Jessberger, Fred H. Gage
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/939e7364d4484ac5b9f6792af0a7191d
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spelling	oai:doaj.org-article:939e7364d4484ac5b9f6792af0a7191d2021-12-02T17:33:16ZA novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons10.1038/s41467-018-05418-82041-1723https://doaj.org/article/939e7364d4484ac5b9f6792af0a7191d2018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05418-8https://doaj.org/toc/2041-1723Single nuclei RNA-seq has been used to characterize transcriptional signature of environment-related activity in cells of the dentate gyrus. Here the authors use this approach to show that whether a neuron will be reactivated in response to re-exposure to a previous environment can be predicted by its transcriptional signature.Baptiste N. JaegerSara B. LinkerSarah L. ParylakJerika J. BarronIryna S. GallinaChristian D. SaavedraConor FitzpatrickChristina K. LimSimon T. SchaferBenjamin LacarSebastian JessbergerFred H. GageNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Baptiste N. Jaeger Sara B. Linker Sarah L. Parylak Jerika J. Barron Iryna S. Gallina Christian D. Saavedra Conor Fitzpatrick Christina K. Lim Simon T. Schafer Benjamin Lacar Sebastian Jessberger Fred H. Gage A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons
description	Single nuclei RNA-seq has been used to characterize transcriptional signature of environment-related activity in cells of the dentate gyrus. Here the authors use this approach to show that whether a neuron will be reactivated in response to re-exposure to a previous environment can be predicted by its transcriptional signature.
format	article
author	Baptiste N. Jaeger Sara B. Linker Sarah L. Parylak Jerika J. Barron Iryna S. Gallina Christian D. Saavedra Conor Fitzpatrick Christina K. Lim Simon T. Schafer Benjamin Lacar Sebastian Jessberger Fred H. Gage
author_facet	Baptiste N. Jaeger Sara B. Linker Sarah L. Parylak Jerika J. Barron Iryna S. Gallina Christian D. Saavedra Conor Fitzpatrick Christina K. Lim Simon T. Schafer Benjamin Lacar Sebastian Jessberger Fred H. Gage
author_sort	Baptiste N. Jaeger
title	A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons
title_short	A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons
title_full	A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons
title_fullStr	A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons
title_full_unstemmed	A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons
title_sort	novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/939e7364d4484ac5b9f6792af0a7191d
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A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons

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