The dilemma: scleroderma renal crisis vs lupus nephritis in a patient with mixed connective tissue disorder

Introduction Mixed connective tissue disorder (MCTD) is a rare connective tissue disorder characterized by features of systemic lupus erythematosus, dermatomyositis, systemic sclerosis, and rheumatoid arthritis. MCTD is associated with an elevated antibody titer to U1 small nuclear ribonucleoprotein...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Nicola Jackson, Shion Betty, James Appiah-Pippim, Yolin Bueno, Sana Makhdumi
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2021
Materias:	systemic lupus erythematosus dermatomyositis systemic sclerosis kasukawa diagnostic criteria mixed connective tissue disorders Internal medicine RC31-1245
Acceso en línea:	https://doaj.org/article/93a38af8b2e3456eabd54f231cfc1738
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:93a38af8b2e3456eabd54f231cfc1738
record_format	dspace
spelling	oai:doaj.org-article:93a38af8b2e3456eabd54f231cfc17382021-11-17T14:21:57ZThe dilemma: scleroderma renal crisis vs lupus nephritis in a patient with mixed connective tissue disorder2000-966610.1080/20009666.2021.1983320https://doaj.org/article/93a38af8b2e3456eabd54f231cfc17382021-11-01T00:00:00Zhttp://dx.doi.org/10.1080/20009666.2021.1983320https://doaj.org/toc/2000-9666Introduction Mixed connective tissue disorder (MCTD) is a rare connective tissue disorder characterized by features of systemic lupus erythematosus, dermatomyositis, systemic sclerosis, and rheumatoid arthritis. MCTD is associated with an elevated antibody titer to U1 small nuclear ribonucleoprotein. Case description: A 49-year-old man presented to the emergency department for evaluation of worsening shortness of breath with associated for bilateral hand pain and swelling associated with morning stiffness which was initially thought to be related to systemic lupus erythematous (SLE). He was also found to have a positive autoantibody, and he was later diagnosed with MCTD complicated by scleroderma renal crisis. Conclusion MCTD is a rare connective tissue disorder with overlapping features of SLE, dermatomyositis, systemic sclerosis, and rheumatoid arthritis. The diagnosis of MCTD requires a high index of suspicion and careful workup. Immunosuppressive therapy is the mainstay of treatment that improves patient outcomes.Nicola JacksonShion BettyJames Appiah-PippimYolin BuenoSana MakhdumiTaylor & Francis Grouparticlesystemic lupus erythematosusdermatomyositissystemic sclerosiskasukawa diagnostic criteriamixed connective tissue disordersInternal medicineRC31-1245ENJournal of Community Hospital Internal Medicine Perspectives, Vol 11, Iss 6, Pp 852-855 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	systemic lupus erythematosus dermatomyositis systemic sclerosis kasukawa diagnostic criteria mixed connective tissue disorders Internal medicine RC31-1245
spellingShingle	systemic lupus erythematosus dermatomyositis systemic sclerosis kasukawa diagnostic criteria mixed connective tissue disorders Internal medicine RC31-1245 Nicola Jackson Shion Betty James Appiah-Pippim Yolin Bueno Sana Makhdumi The dilemma: scleroderma renal crisis vs lupus nephritis in a patient with mixed connective tissue disorder
description	Introduction Mixed connective tissue disorder (MCTD) is a rare connective tissue disorder characterized by features of systemic lupus erythematosus, dermatomyositis, systemic sclerosis, and rheumatoid arthritis. MCTD is associated with an elevated antibody titer to U1 small nuclear ribonucleoprotein. Case description: A 49-year-old man presented to the emergency department for evaluation of worsening shortness of breath with associated for bilateral hand pain and swelling associated with morning stiffness which was initially thought to be related to systemic lupus erythematous (SLE). He was also found to have a positive autoantibody, and he was later diagnosed with MCTD complicated by scleroderma renal crisis. Conclusion MCTD is a rare connective tissue disorder with overlapping features of SLE, dermatomyositis, systemic sclerosis, and rheumatoid arthritis. The diagnosis of MCTD requires a high index of suspicion and careful workup. Immunosuppressive therapy is the mainstay of treatment that improves patient outcomes.
format	article
author	Nicola Jackson Shion Betty James Appiah-Pippim Yolin Bueno Sana Makhdumi
author_facet	Nicola Jackson Shion Betty James Appiah-Pippim Yolin Bueno Sana Makhdumi
author_sort	Nicola Jackson
title	The dilemma: scleroderma renal crisis vs lupus nephritis in a patient with mixed connective tissue disorder
title_short	The dilemma: scleroderma renal crisis vs lupus nephritis in a patient with mixed connective tissue disorder
title_full	The dilemma: scleroderma renal crisis vs lupus nephritis in a patient with mixed connective tissue disorder
title_fullStr	The dilemma: scleroderma renal crisis vs lupus nephritis in a patient with mixed connective tissue disorder
title_full_unstemmed	The dilemma: scleroderma renal crisis vs lupus nephritis in a patient with mixed connective tissue disorder
title_sort	dilemma: scleroderma renal crisis vs lupus nephritis in a patient with mixed connective tissue disorder
publisher	Taylor & Francis Group
publishDate	2021
url	https://doaj.org/article/93a38af8b2e3456eabd54f231cfc1738
work_keys_str_mv	AT nicolajackson thedilemmasclerodermarenalcrisisvslupusnephritisinapatientwithmixedconnectivetissuedisorder AT shionbetty thedilemmasclerodermarenalcrisisvslupusnephritisinapatientwithmixedconnectivetissuedisorder AT jamesappiahpippim thedilemmasclerodermarenalcrisisvslupusnephritisinapatientwithmixedconnectivetissuedisorder AT yolinbueno thedilemmasclerodermarenalcrisisvslupusnephritisinapatientwithmixedconnectivetissuedisorder AT sanamakhdumi thedilemmasclerodermarenalcrisisvslupusnephritisinapatientwithmixedconnectivetissuedisorder AT nicolajackson dilemmasclerodermarenalcrisisvslupusnephritisinapatientwithmixedconnectivetissuedisorder AT shionbetty dilemmasclerodermarenalcrisisvslupusnephritisinapatientwithmixedconnectivetissuedisorder AT jamesappiahpippim dilemmasclerodermarenalcrisisvslupusnephritisinapatientwithmixedconnectivetissuedisorder AT yolinbueno dilemmasclerodermarenalcrisisvslupusnephritisinapatientwithmixedconnectivetissuedisorder AT sanamakhdumi dilemmasclerodermarenalcrisisvslupusnephritisinapatientwithmixedconnectivetissuedisorder
_version_	1718425496555880448

The dilemma: scleroderma renal crisis vs lupus nephritis in a patient with mixed connective tissue disorder

Ejemplares similares