Is there an optimal management for localized prostate cancer?

Jaspreet Singh , Edouard J Trabulsi, Leonard G GomellaDepartment of Urology Kimmel Cancer Center Thomas Jefferson University Philadelphia, PA, USAAbstract: Widespread screening with prostate-specific antigen (PSA) has led to a significant increase in the detection of early stage, clinically localize...

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Autores principales: Jaspreet Singh, Edouard J Trabulsi, Leonard G Gomella
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2010
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Acceso en línea:https://doaj.org/article/93a5d75912924df8be875260bb5326b3
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spelling oai:doaj.org-article:93a5d75912924df8be875260bb5326b32021-12-02T06:58:43ZIs there an optimal management for localized prostate cancer?1178-1998https://doaj.org/article/93a5d75912924df8be875260bb5326b32010-07-01T00:00:00Zhttps://www.dovepress.com/is-there-an-optimal-management-for-localized-prostate-cancer-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Jaspreet Singh , Edouard J Trabulsi, Leonard G GomellaDepartment of Urology Kimmel Cancer Center Thomas Jefferson University Philadelphia, PA, USAAbstract: Widespread screening with prostate-specific antigen (PSA) has led to a significant increase in the detection of early stage, clinically localized prostate cancer (CaP). Various ­treatment options for localized CaP are discussed in this review article including active ­surveillance, radical prostatectomy, radiation therapy, and cyrotherapy. The paucity of high-level evidence adds a considerable amount of controversy when choosing the “optimal” ­intervention, for both the treating physician and the patient. The long time course of CaP intervention outcomes, combined with continuing modifications in treatments, further complicate the ­matter. Lacking randomized trials that compare treatment options, this review article attempts to summarize the different treatment options and associated side-effects, including effects on health-related quality of life, from current published literature.Keywords: prostate cancer, PSA, detectionJaspreet SinghEdouard J TrabulsiLeonard G GomellaDove Medical PressarticleManagementProstate CancerGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 5, Pp 187-197 (2010)
institution DOAJ
collection DOAJ
language EN
topic Management
Prostate Cancer
Geriatrics
RC952-954.6
spellingShingle Management
Prostate Cancer
Geriatrics
RC952-954.6
Jaspreet Singh
Edouard J Trabulsi
Leonard G Gomella
Is there an optimal management for localized prostate cancer?
description Jaspreet Singh , Edouard J Trabulsi, Leonard G GomellaDepartment of Urology Kimmel Cancer Center Thomas Jefferson University Philadelphia, PA, USAAbstract: Widespread screening with prostate-specific antigen (PSA) has led to a significant increase in the detection of early stage, clinically localized prostate cancer (CaP). Various ­treatment options for localized CaP are discussed in this review article including active ­surveillance, radical prostatectomy, radiation therapy, and cyrotherapy. The paucity of high-level evidence adds a considerable amount of controversy when choosing the “optimal” ­intervention, for both the treating physician and the patient. The long time course of CaP intervention outcomes, combined with continuing modifications in treatments, further complicate the ­matter. Lacking randomized trials that compare treatment options, this review article attempts to summarize the different treatment options and associated side-effects, including effects on health-related quality of life, from current published literature.Keywords: prostate cancer, PSA, detection
format article
author Jaspreet Singh
Edouard J Trabulsi
Leonard G Gomella
author_facet Jaspreet Singh
Edouard J Trabulsi
Leonard G Gomella
author_sort Jaspreet Singh
title Is there an optimal management for localized prostate cancer?
title_short Is there an optimal management for localized prostate cancer?
title_full Is there an optimal management for localized prostate cancer?
title_fullStr Is there an optimal management for localized prostate cancer?
title_full_unstemmed Is there an optimal management for localized prostate cancer?
title_sort is there an optimal management for localized prostate cancer?
publisher Dove Medical Press
publishDate 2010
url https://doaj.org/article/93a5d75912924df8be875260bb5326b3
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