Is there an optimal management for localized prostate cancer?
Jaspreet Singh , Edouard J Trabulsi, Leonard G GomellaDepartment of Urology Kimmel Cancer Center Thomas Jefferson University Philadelphia, PA, USAAbstract: Widespread screening with prostate-specific antigen (PSA) has led to a significant increase in the detection of early stage, clinically localize...
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Dove Medical Press
2010
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oai:doaj.org-article:93a5d75912924df8be875260bb5326b32021-12-02T06:58:43ZIs there an optimal management for localized prostate cancer?1178-1998https://doaj.org/article/93a5d75912924df8be875260bb5326b32010-07-01T00:00:00Zhttps://www.dovepress.com/is-there-an-optimal-management-for-localized-prostate-cancer-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Jaspreet Singh , Edouard J Trabulsi, Leonard G GomellaDepartment of Urology Kimmel Cancer Center Thomas Jefferson University Philadelphia, PA, USAAbstract: Widespread screening with prostate-specific antigen (PSA) has led to a significant increase in the detection of early stage, clinically localized prostate cancer (CaP). Various ­treatment options for localized CaP are discussed in this review article including active ­surveillance, radical prostatectomy, radiation therapy, and cyrotherapy. The paucity of high-level evidence adds a considerable amount of controversy when choosing the “optimal” ­intervention, for both the treating physician and the patient. The long time course of CaP intervention outcomes, combined with continuing modifications in treatments, further complicate the ­matter. Lacking randomized trials that compare treatment options, this review article attempts to summarize the different treatment options and associated side-effects, including effects on health-related quality of life, from current published literature.Keywords: prostate cancer, PSA, detectionJaspreet SinghEdouard J TrabulsiLeonard G GomellaDove Medical PressarticleManagementProstate CancerGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 5, Pp 187-197 (2010) |
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Management Prostate Cancer Geriatrics RC952-954.6 |
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Management Prostate Cancer Geriatrics RC952-954.6 Jaspreet Singh Edouard J Trabulsi Leonard G Gomella Is there an optimal management for localized prostate cancer? |
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Jaspreet Singh , Edouard J Trabulsi, Leonard G GomellaDepartment of Urology Kimmel Cancer Center Thomas Jefferson University Philadelphia, PA, USAAbstract: Widespread screening with prostate-specific antigen (PSA) has led to a significant increase in the detection of early stage, clinically localized prostate cancer (CaP). Various ­treatment options for localized CaP are discussed in this review article including active ­surveillance, radical prostatectomy, radiation therapy, and cyrotherapy. The paucity of high-level evidence adds a considerable amount of controversy when choosing the “optimal” ­intervention, for both the treating physician and the patient. The long time course of CaP intervention outcomes, combined with continuing modifications in treatments, further complicate the ­matter. Lacking randomized trials that compare treatment options, this review article attempts to summarize the different treatment options and associated side-effects, including effects on health-related quality of life, from current published literature.Keywords: prostate cancer, PSA, detection |
format |
article |
author |
Jaspreet Singh Edouard J Trabulsi Leonard G Gomella |
author_facet |
Jaspreet Singh Edouard J Trabulsi Leonard G Gomella |
author_sort |
Jaspreet Singh |
title |
Is there an optimal management for localized prostate cancer? |
title_short |
Is there an optimal management for localized prostate cancer? |
title_full |
Is there an optimal management for localized prostate cancer? |
title_fullStr |
Is there an optimal management for localized prostate cancer? |
title_full_unstemmed |
Is there an optimal management for localized prostate cancer? |
title_sort |
is there an optimal management for localized prostate cancer? |
publisher |
Dove Medical Press |
publishDate |
2010 |
url |
https://doaj.org/article/93a5d75912924df8be875260bb5326b3 |
work_keys_str_mv |
AT jaspreetsingh isthereanoptimalmanagementforlocalizedprostatecancer AT edouardjtrabulsi isthereanoptimalmanagementforlocalizedprostatecancer AT leonardggomella isthereanoptimalmanagementforlocalizedprostatecancer |
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1718399648530432000 |