Genetic markers enhance coronary risk prediction in men: the MORGAM prospective cohorts.

Genetic markers enhance coronary risk prediction in men: the MORGAM prospective cohorts.

<h4>Background</h4>More accurate coronary heart disease (CHD) prediction, specifically in middle-aged men, is needed to reduce the burden of disease more effectively. We hypothesised that a multilocus genetic risk score could refine CHD prediction beyond classic risk scores and obtain mo...

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Autores principales: Maria F Hughes, Olli Saarela, Jan Stritzke, Frank Kee, Kaisa Silander, Norman Klopp, Jukka Kontto, Juha Karvanen, Christina Willenborg, Veikko Salomaa, Jarmo Virtamo, Phillippe Amouyel, Dominique Arveiler, Jean Ferrières, Per-Gunner Wiklund, Jens Baumert, Barbara Thorand, Patrick Diemert, David-Alexandre Trégouët, Christian Hengstenberg, Annette Peters, Alun Evans, Wolfgang Koenig, Jeanette Erdmann, Nilesh J Samani, Kari Kuulasmaa, Heribert Schunkert
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/93aa9ce69c34452b95c91a1125596ec4
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