Nematode-derived proteins suppress proliferation and cytokine production of antigen-specific T cells via induction of cell death.

In order to establish long-lasting infections in their mammalian host, filarial nematodes have developed sophisticated strategies to dampen their host's immune response. Proteins that are actively secreted by the parasites have been shown to induce the expansion of regulatory T cells and to dir...

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Autores principales: Wiebke Hartmann, Yannick Brenz, Manchang Tanyi Kingsley, Irene Ajonina-Ekoti, Norbert W Brattig, Eva Liebau, Minka Breloer
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/93b24363043040a1a52428daa55f3ecb
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