Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes
Bioorthogonal diversification of peptides is generally dependent on impractical prefunctionalization methods. Here, the authors develop a manganese(I)-catalyzed C–H fluorescent labeling with BODIPY probes, which enables the development of activatable fluorophores to image cell function.
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Nature Portfolio
2021
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oai:doaj.org-article:93b52903be4747fead66811972b504c12021-12-02T17:47:02ZChemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes10.1038/s41467-021-23462-92041-1723https://doaj.org/article/93b52903be4747fead66811972b504c12021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23462-9https://doaj.org/toc/2041-1723Bioorthogonal diversification of peptides is generally dependent on impractical prefunctionalization methods. Here, the authors develop a manganese(I)-catalyzed C–H fluorescent labeling with BODIPY probes, which enables the development of activatable fluorophores to image cell function.Nikolaos KaplanerisJongwoo SonLorena Mendive-TapiaAdelina KoppNicole D. BarthIsaac MakssoMarc VendrellLutz AckermannNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021) |
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Science Q Nikolaos Kaplaneris Jongwoo Son Lorena Mendive-Tapia Adelina Kopp Nicole D. Barth Isaac Maksso Marc Vendrell Lutz Ackermann Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes |
description |
Bioorthogonal diversification of peptides is generally dependent on impractical prefunctionalization methods. Here, the authors develop a manganese(I)-catalyzed C–H fluorescent labeling with BODIPY probes, which enables the development of activatable fluorophores to image cell function. |
format |
article |
author |
Nikolaos Kaplaneris Jongwoo Son Lorena Mendive-Tapia Adelina Kopp Nicole D. Barth Isaac Maksso Marc Vendrell Lutz Ackermann |
author_facet |
Nikolaos Kaplaneris Jongwoo Son Lorena Mendive-Tapia Adelina Kopp Nicole D. Barth Isaac Maksso Marc Vendrell Lutz Ackermann |
author_sort |
Nikolaos Kaplaneris |
title |
Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes |
title_short |
Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes |
title_full |
Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes |
title_fullStr |
Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes |
title_full_unstemmed |
Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes |
title_sort |
chemodivergent manganese-catalyzed c–h activation: modular synthesis of fluorogenic probes |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/93b52903be4747fead66811972b504c1 |
work_keys_str_mv |
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_version_ |
1718379541187002368 |