Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes

Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes

Bioorthogonal diversification of peptides is generally dependent on impractical prefunctionalization methods. Here, the authors develop a manganese(I)-catalyzed C–H fluorescent labeling with BODIPY probes, which enables the development of activatable fluorophores to image cell function.

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Autores principales: Nikolaos Kaplaneris, Jongwoo Son, Lorena Mendive-Tapia, Adelina Kopp, Nicole D. Barth, Isaac Maksso, Marc Vendrell, Lutz Ackermann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/93b52903be4747fead66811972b504c1
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