Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes
Bioorthogonal diversification of peptides is generally dependent on impractical prefunctionalization methods. Here, the authors develop a manganese(I)-catalyzed C–H fluorescent labeling with BODIPY probes, which enables the development of activatable fluorophores to image cell function.
Saved in:
| Main Authors: | Nikolaos Kaplaneris, Jongwoo Son, Lorena Mendive-Tapia, Adelina Kopp, Nicole D. Barth, Isaac Maksso, Marc Vendrell, Lutz Ackermann |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/93b52903be4747fead66811972b504c1 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Late-stage peptide C–H alkylation for bioorthogonal C–H activation featuring solid phase peptide synthesis
by: Alexandra Schischko, et al.
Published: (2019) -
A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis
by: Nicole D. Barth, et al.
Published: (2020) -
Chemodivergent assembly of ortho-functionalized phenols with tunable selectivity via rhodium(III)-catalyzed and solvent-controlled C-H activation
by: Haiman Zhang, et al.
Published: (2021) -
Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue
by: Lorena Mendive-Tapia, et al.
Published: (2016) -
Chemodivergent transformations of amides using gem-diborylalkanes as pro-nucleophiles
by: Wei Sun, et al.
Published: (2020)