Single-nucleotide conservation state annotation of the SARS-CoV-2 genome
Kwon and Ernst applied the comparative genomics method, ConsHMM, to the multi-strain alignments of different coronaviruses in order to annotate every base of the SARS-CoV-2 genome with conservation states. The conservation states reflect sequence alignment patterns among different coronaviruses, whi...
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| Autores principales: | , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/93d5a587959f4192b539707ede788392 |
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| Sumario: | Kwon and Ernst applied the comparative genomics method, ConsHMM, to the multi-strain alignments of different coronaviruses in order to annotate every base of the SARS-CoV-2 genome with conservation states. The conservation states reflect sequence alignment patterns among different coronaviruses, which would assist with understanding the functional consequences of SARS-CoV-2 mutations. |
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