Single-nucleotide conservation state annotation of the SARS-CoV-2 genome

Kwon and Ernst applied the comparative genomics method, ConsHMM, to the multi-strain alignments of different coronaviruses in order to annotate every base of the SARS-CoV-2 genome with conservation states. The conservation states reflect sequence alignment patterns among different coronaviruses, whi...

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Autores principales:	Soo Bin Kwon, Jason Ernst
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/93d5a587959f4192b539707ede788392
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spelling	oai:doaj.org-article:93d5a587959f4192b539707ede7883922021-12-02T15:02:48ZSingle-nucleotide conservation state annotation of the SARS-CoV-2 genome10.1038/s42003-021-02231-w2399-3642https://doaj.org/article/93d5a587959f4192b539707ede7883922021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02231-whttps://doaj.org/toc/2399-3642Kwon and Ernst applied the comparative genomics method, ConsHMM, to the multi-strain alignments of different coronaviruses in order to annotate every base of the SARS-CoV-2 genome with conservation states. The conservation states reflect sequence alignment patterns among different coronaviruses, which would assist with understanding the functional consequences of SARS-CoV-2 mutations.Soo Bin KwonJason ErnstNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Soo Bin Kwon Jason Ernst Single-nucleotide conservation state annotation of the SARS-CoV-2 genome
description	Kwon and Ernst applied the comparative genomics method, ConsHMM, to the multi-strain alignments of different coronaviruses in order to annotate every base of the SARS-CoV-2 genome with conservation states. The conservation states reflect sequence alignment patterns among different coronaviruses, which would assist with understanding the functional consequences of SARS-CoV-2 mutations.
format	article
author	Soo Bin Kwon Jason Ernst
author_facet	Soo Bin Kwon Jason Ernst
author_sort	Soo Bin Kwon
title	Single-nucleotide conservation state annotation of the SARS-CoV-2 genome
title_short	Single-nucleotide conservation state annotation of the SARS-CoV-2 genome
title_full	Single-nucleotide conservation state annotation of the SARS-CoV-2 genome
title_fullStr	Single-nucleotide conservation state annotation of the SARS-CoV-2 genome
title_full_unstemmed	Single-nucleotide conservation state annotation of the SARS-CoV-2 genome
title_sort	single-nucleotide conservation state annotation of the sars-cov-2 genome
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/93d5a587959f4192b539707ede788392
work_keys_str_mv	AT soobinkwon singlenucleotideconservationstateannotationofthesarscov2genome AT jasonernst singlenucleotideconservationstateannotationofthesarscov2genome
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Single-nucleotide conservation state annotation of the SARS-CoV-2 genome

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