Innate T-αβ lymphocytes as new immunological components of anti-tumoral “off-target” effects of the tyrosine kinase inhibitor dasatinib

Abstract Kinase inhibitors hold great potential as targeted therapy against malignant cells. Among them, the tyrosine kinase inhibitor dasatinib is known for a number of clinically relevant off-target actions, attributed in part to effects on components of the immune system, especially conventional...

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Bibliographic Details
Main Authors: Alice Barbarin, Myriam Abdallah, Lucie Lefèvre, Nathalie Piccirilli, Emilie Cayssials, Lydia Roy, Jean-Marc Gombert, André Herbelin
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
R
Q
Online Access:https://doaj.org/article/93d95eabd8174e51acc184d4b1943df3
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