Case Report: A Rare Case of Lupus Nephritis Associated With Mantle Cell Lymphoma

In this research, we described a very rare case of secondary lupus nephritis associated with B-cell lymphoma. An 84-year-old man was hospitalized at our institute for lower extremity edema persisting for over 2 months. He was diagnosed with systemic lupus erythematosus based on clinical and laborato...

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Autores principales: Daorina Bao, Ying Tan, Xiaojuan Yu, Bingjie Wang, Hui Wang, Rong Xu, Fude Zhou, Minghui Zhao
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Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/93e176f6bf9e4262897baf1cc4ef8173
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spelling oai:doaj.org-article:93e176f6bf9e4262897baf1cc4ef81732021-12-01T12:27:10ZCase Report: A Rare Case of Lupus Nephritis Associated With Mantle Cell Lymphoma2296-858X10.3389/fmed.2021.759279https://doaj.org/article/93e176f6bf9e4262897baf1cc4ef81732021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fmed.2021.759279/fullhttps://doaj.org/toc/2296-858XIn this research, we described a very rare case of secondary lupus nephritis associated with B-cell lymphoma. An 84-year-old man was hospitalized at our institute for lower extremity edema persisting for over 2 months. He was diagnosed with systemic lupus erythematosus based on clinical and laboratory criteria, which showed impaired renal function and nephrotic syndrome with predominant hematuria. Renal biopsy showed IV+V lupus nephritis with highly infiltrated lymphoid cells in the kidney. Secondary lupus nephritis was suspected based on the possible pathogenesis of glomerular injury due to mantle cell lymphoma. Low-dose dexamethasone, rituximab, and lenalidomide were immediately started on the patient, and his renal function was improved after the first cycle of chemotherapy.Daorina BaoDaorina BaoDaorina BaoDaorina BaoDaorina BaoYing TanYing TanYing TanYing TanYing TanXiaojuan YuXiaojuan YuXiaojuan YuXiaojuan YuXiaojuan YuBingjie WangHui WangRong XuRong XuRong XuRong XuRong XuFude ZhouFude ZhouFude ZhouFude ZhouFude ZhouMinghui ZhaoMinghui ZhaoMinghui ZhaoMinghui ZhaoMinghui ZhaoMinghui ZhaoFrontiers Media S.A.articlelupus nephritismantle cell lymphomasecondary SLEnon-Hodgkin lymphomaacute kidney injuryMedicine (General)R5-920ENFrontiers in Medicine, Vol 8 (2021)
institution DOAJ
collection DOAJ
language EN
topic lupus nephritis
mantle cell lymphoma
secondary SLE
non-Hodgkin lymphoma
acute kidney injury
Medicine (General)
R5-920
spellingShingle lupus nephritis
mantle cell lymphoma
secondary SLE
non-Hodgkin lymphoma
acute kidney injury
Medicine (General)
R5-920
Daorina Bao
Daorina Bao
Daorina Bao
Daorina Bao
Daorina Bao
Ying Tan
Ying Tan
Ying Tan
Ying Tan
Ying Tan
Xiaojuan Yu
Xiaojuan Yu
Xiaojuan Yu
Xiaojuan Yu
Xiaojuan Yu
Bingjie Wang
Hui Wang
Rong Xu
Rong Xu
Rong Xu
Rong Xu
Rong Xu
Fude Zhou
Fude Zhou
Fude Zhou
Fude Zhou
Fude Zhou
Minghui Zhao
Minghui Zhao
Minghui Zhao
Minghui Zhao
Minghui Zhao
Minghui Zhao
Case Report: A Rare Case of Lupus Nephritis Associated With Mantle Cell Lymphoma
description In this research, we described a very rare case of secondary lupus nephritis associated with B-cell lymphoma. An 84-year-old man was hospitalized at our institute for lower extremity edema persisting for over 2 months. He was diagnosed with systemic lupus erythematosus based on clinical and laboratory criteria, which showed impaired renal function and nephrotic syndrome with predominant hematuria. Renal biopsy showed IV+V lupus nephritis with highly infiltrated lymphoid cells in the kidney. Secondary lupus nephritis was suspected based on the possible pathogenesis of glomerular injury due to mantle cell lymphoma. Low-dose dexamethasone, rituximab, and lenalidomide were immediately started on the patient, and his renal function was improved after the first cycle of chemotherapy.
format article
author Daorina Bao
Daorina Bao
Daorina Bao
Daorina Bao
Daorina Bao
Ying Tan
Ying Tan
Ying Tan
Ying Tan
Ying Tan
Xiaojuan Yu
Xiaojuan Yu
Xiaojuan Yu
Xiaojuan Yu
Xiaojuan Yu
Bingjie Wang
Hui Wang
Rong Xu
Rong Xu
Rong Xu
Rong Xu
Rong Xu
Fude Zhou
Fude Zhou
Fude Zhou
Fude Zhou
Fude Zhou
Minghui Zhao
Minghui Zhao
Minghui Zhao
Minghui Zhao
Minghui Zhao
Minghui Zhao
author_facet Daorina Bao
Daorina Bao
Daorina Bao
Daorina Bao
Daorina Bao
Ying Tan
Ying Tan
Ying Tan
Ying Tan
Ying Tan
Xiaojuan Yu
Xiaojuan Yu
Xiaojuan Yu
Xiaojuan Yu
Xiaojuan Yu
Bingjie Wang
Hui Wang
Rong Xu
Rong Xu
Rong Xu
Rong Xu
Rong Xu
Fude Zhou
Fude Zhou
Fude Zhou
Fude Zhou
Fude Zhou
Minghui Zhao
Minghui Zhao
Minghui Zhao
Minghui Zhao
Minghui Zhao
Minghui Zhao
author_sort Daorina Bao
title Case Report: A Rare Case of Lupus Nephritis Associated With Mantle Cell Lymphoma
title_short Case Report: A Rare Case of Lupus Nephritis Associated With Mantle Cell Lymphoma
title_full Case Report: A Rare Case of Lupus Nephritis Associated With Mantle Cell Lymphoma
title_fullStr Case Report: A Rare Case of Lupus Nephritis Associated With Mantle Cell Lymphoma
title_full_unstemmed Case Report: A Rare Case of Lupus Nephritis Associated With Mantle Cell Lymphoma
title_sort case report: a rare case of lupus nephritis associated with mantle cell lymphoma
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/93e176f6bf9e4262897baf1cc4ef8173
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