Laser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma

(1) Background: The incidence of papillary thyroid cancers is increasing. Papillary neoplasm metastasizes to the central and lateral lymph nodes of the neck. The recurrence rate is less than 30%. The gold standard of treatment for lymph node recurrences is surgery, but surgery is burdened by a high...

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Autores principales:	Chiara Offi, Claudia Misso, Giovanni Antonelli, Maria Grazia Esposito, Umberto Brancaccio, Stefano Spiezia
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	thyroid carcinoma laser ablation papillary thyroid carcinoma lymph nodes metastases recurrence Medicine R
Acceso en línea:	https://doaj.org/article/93e1e6eab1fe45aeb7185218a89467bb
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spelling	oai:doaj.org-article:93e1e6eab1fe45aeb7185218a89467bb2021-11-25T18:01:30ZLaser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma10.3390/jcm102252952077-0383https://doaj.org/article/93e1e6eab1fe45aeb7185218a89467bb2021-11-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/22/5295https://doaj.org/toc/2077-0383(1) Background: The incidence of papillary thyroid cancers is increasing. Papillary neoplasm metastasizes to the central and lateral lymph nodes of the neck. The recurrence rate is less than 30%. The gold standard of treatment for lymph node recurrences is surgery, but surgery is burdened by a high rate of complications. Therefore, laser ablation of recurrent lymph nodes has been recognized as an alternative treatment with minimal invasiveness, a low complication rate and a curative effect. (2) Methods: We analyzed 10 patients who underwent a total thyroidectomy and metabolic radiotherapy and who developed a lymph node recurrence in the laterocervical compartment in the following 12–18 months. (3) Results: Patients developed lymph node recurrence at IV and Vb levels in 70% and 30% of cases, respectively. All patients were treated with a single laser ablative session. Hydrodissection was performed in all patients. The energy delivered was 1120 ± 159.3 Joules and 3–4 Watts in 362 ± 45.7 s. No complications were reported. All patients underwent a 6-month follow-up. A volumetric reduction of 40.12 ± 2.2%, 49.1 ± 2.13% and 59.8 ± 3.05%, respectively at 1-, 3- and 6-months of follow-up was reported. (4) Conclusions: At 6 months, a fine needle aspiration was performed, which was negative for malignant cells and negative for a dosage of Thyroglobulin in eluate. The laser ablation is an effective alternative to surgical treatment.Chiara OffiClaudia MissoGiovanni AntonelliMaria Grazia EspositoUmberto BrancaccioStefano SpieziaMDPI AGarticlethyroid carcinomalaser ablationpapillary thyroid carcinomalymph nodes metastasesrecurrenceMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5295, p 5295 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	thyroid carcinoma laser ablation papillary thyroid carcinoma lymph nodes metastases recurrence Medicine R
spellingShingle	thyroid carcinoma laser ablation papillary thyroid carcinoma lymph nodes metastases recurrence Medicine R Chiara Offi Claudia Misso Giovanni Antonelli Maria Grazia Esposito Umberto Brancaccio Stefano Spiezia Laser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma
description	(1) Background: The incidence of papillary thyroid cancers is increasing. Papillary neoplasm metastasizes to the central and lateral lymph nodes of the neck. The recurrence rate is less than 30%. The gold standard of treatment for lymph node recurrences is surgery, but surgery is burdened by a high rate of complications. Therefore, laser ablation of recurrent lymph nodes has been recognized as an alternative treatment with minimal invasiveness, a low complication rate and a curative effect. (2) Methods: We analyzed 10 patients who underwent a total thyroidectomy and metabolic radiotherapy and who developed a lymph node recurrence in the laterocervical compartment in the following 12–18 months. (3) Results: Patients developed lymph node recurrence at IV and Vb levels in 70% and 30% of cases, respectively. All patients were treated with a single laser ablative session. Hydrodissection was performed in all patients. The energy delivered was 1120 ± 159.3 Joules and 3–4 Watts in 362 ± 45.7 s. No complications were reported. All patients underwent a 6-month follow-up. A volumetric reduction of 40.12 ± 2.2%, 49.1 ± 2.13% and 59.8 ± 3.05%, respectively at 1-, 3- and 6-months of follow-up was reported. (4) Conclusions: At 6 months, a fine needle aspiration was performed, which was negative for malignant cells and negative for a dosage of Thyroglobulin in eluate. The laser ablation is an effective alternative to surgical treatment.
format	article
author	Chiara Offi Claudia Misso Giovanni Antonelli Maria Grazia Esposito Umberto Brancaccio Stefano Spiezia
author_facet	Chiara Offi Claudia Misso Giovanni Antonelli Maria Grazia Esposito Umberto Brancaccio Stefano Spiezia
author_sort	Chiara Offi
title	Laser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma
title_short	Laser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma
title_full	Laser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma
title_fullStr	Laser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma
title_full_unstemmed	Laser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma
title_sort	laser ablation treatment of recurrent lymph node metastases from papillary thyroid carcinoma
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/93e1e6eab1fe45aeb7185218a89467bb
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Laser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma

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