Ion mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain

Sterol lipids are crucial for maintaining proper brain function. Here, the authors combine ion mobility-mass spectrometry and machine learning to assemble a sterol lipid library and characterize differences in sterol lipids across ten brain regions and two age groups in mice.

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Autores principales:	Tongzhou Li, Yandong Yin, Zhiwei Zhou, Jiaqian Qiu, Wenbin Liu, Xueting Zhang, Kaiwen He, Yuping Cai, Zheng-Jiang Zhu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/93e2745d67af43f4871d194c83d08ba0
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spelling	oai:doaj.org-article:93e2745d67af43f4871d194c83d08ba02021-12-02T15:33:16ZIon mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain10.1038/s41467-021-24672-x2041-1723https://doaj.org/article/93e2745d67af43f4871d194c83d08ba02021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24672-xhttps://doaj.org/toc/2041-1723Sterol lipids are crucial for maintaining proper brain function. Here, the authors combine ion mobility-mass spectrometry and machine learning to assemble a sterol lipid library and characterize differences in sterol lipids across ten brain regions and two age groups in mice.Tongzhou LiYandong YinZhiwei ZhouJiaqian QiuWenbin LiuXueting ZhangKaiwen HeYuping CaiZheng-Jiang ZhuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tongzhou Li Yandong Yin Zhiwei Zhou Jiaqian Qiu Wenbin Liu Xueting Zhang Kaiwen He Yuping Cai Zheng-Jiang Zhu Ion mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain
description	Sterol lipids are crucial for maintaining proper brain function. Here, the authors combine ion mobility-mass spectrometry and machine learning to assemble a sterol lipid library and characterize differences in sterol lipids across ten brain regions and two age groups in mice.
format	article
author	Tongzhou Li Yandong Yin Zhiwei Zhou Jiaqian Qiu Wenbin Liu Xueting Zhang Kaiwen He Yuping Cai Zheng-Jiang Zhu
author_facet	Tongzhou Li Yandong Yin Zhiwei Zhou Jiaqian Qiu Wenbin Liu Xueting Zhang Kaiwen He Yuping Cai Zheng-Jiang Zhu
author_sort	Tongzhou Li
title	Ion mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain
title_short	Ion mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain
title_full	Ion mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain
title_fullStr	Ion mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain
title_full_unstemmed	Ion mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain
title_sort	ion mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/93e2745d67af43f4871d194c83d08ba0
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Ion mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain

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