Single-cell RNA sequencing of peripheral blood mononuclear cells from acute Kawasaki disease patients

Single-cell RNA sequencing of peripheral blood mononuclear cells from acute Kawasaki disease patients

Immune cell changes are associated with Kawasaki disease (KD) pathogenesis. Here, using single cell RNA sequencing of PBMC, the authors show monocyte inflammatory genes are over-expressed in KD and TCR and BCR clonotype sequences show oligoclonal expansions after intravenous immunoglobulin therapy.

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Autores principales: Zhen Wang, Lijian Xie, Guohui Ding, Sirui Song, Liqin Chen, Guang Li, Min Xia, Dingding Han, Yue Zheng, Jia Liu, Tingting Xiao, Hong Zhang, Yujuan Huang, Yixue Li, Min Huang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
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Acceso en línea:https://doaj.org/article/93ebaddff46c45799b701c2eb870db1f
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