Clinical and Histopathological Findings in 26 Patients with Oral Lichenoid Lesions

BACKGROUND AND OBJECTIVE: Lichen planus is an immunologically mediated disease that causes degeneration of keratinocytes in the oral mucosa. Lichenoid lesions are a group of lesions with different etiologic factors and similar clinical and histopathological features. This study was done for evaluati...

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Autores principales: M Seyedmajidi, M Motallebnejad, R Foroughi, F Aslani
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Publicado: Babol University of Medical Sciences 2010
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spelling oai:doaj.org-article:93f04c585e9e41a4a16ccc8f12105fcd2021-11-10T09:00:30ZClinical and Histopathological Findings in 26 Patients with Oral Lichenoid Lesions1561-41072251-7170https://doaj.org/article/93f04c585e9e41a4a16ccc8f12105fcd2010-08-01T00:00:00Zhttp://jbums.org/article-1-3635-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Lichen planus is an immunologically mediated disease that causes degeneration of keratinocytes in the oral mucosa. Lichenoid lesions are a group of lesions with different etiologic factors and similar clinical and histopathological features. This study was done for evaluation of clinical and histopathological findings and the frequency of idiopathic lichen planus among patients with oral lichenoid lesions who referred to Babol dental faculty.METHODS: This cross-sectional study was performed on the 26 patients affected by oral lichenoid lesions who referred to oral disease department of Babol dental faculty, Babol, Iran during 2007-2009. All patients were examined about some determinants such as age, sex, skin lesion affecting, systemic disease, drug usage, kind and location of lesions.FINDINGS: The mean age of the patients was 42.8±12.4. 30.8% (8 cases) of population were men and 69.2% (18 cases) were women. Fourth, fifth and sixth decades were the most commonly affected decades. 46.2% (12) of patients had systemic disease and 3 (11.5%) of patients had a skin lesion. Fourteen (53.8%) of patients use drug for systemic disease. Nineteen (73%) of patients reported exact time for duration of lesions. The most common affected area was buccal mucosa and the most common lesion that reported was reticular type. Four (15.4%) of patients showed dysplasia on their oral lesions.CONCLUSION: Due to higher incidence of oral lichenoid lesions in 30 year old to 60 year old women, clinical examination of oral mucosa must be considered in middle aged women. Also considerable percentage of dysplastic changes in oral lichenoid lesions reveals that these patients must be followed up.M SeyedmajidiM MotallebnejadR Foroughi,F AslaniBabol University of Medical Sciencesarticlelichen planuslichenoid reactionoral mucosaMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 12, Iss 3, Pp 72-78 (2010)
institution DOAJ
collection DOAJ
language EN
FA
topic lichen planus
lichenoid reaction
oral mucosa
Medicine
R
Medicine (General)
R5-920
spellingShingle lichen planus
lichenoid reaction
oral mucosa
Medicine
R
Medicine (General)
R5-920
M Seyedmajidi
M Motallebnejad
R Foroughi,
F Aslani
Clinical and Histopathological Findings in 26 Patients with Oral Lichenoid Lesions
description BACKGROUND AND OBJECTIVE: Lichen planus is an immunologically mediated disease that causes degeneration of keratinocytes in the oral mucosa. Lichenoid lesions are a group of lesions with different etiologic factors and similar clinical and histopathological features. This study was done for evaluation of clinical and histopathological findings and the frequency of idiopathic lichen planus among patients with oral lichenoid lesions who referred to Babol dental faculty.METHODS: This cross-sectional study was performed on the 26 patients affected by oral lichenoid lesions who referred to oral disease department of Babol dental faculty, Babol, Iran during 2007-2009. All patients were examined about some determinants such as age, sex, skin lesion affecting, systemic disease, drug usage, kind and location of lesions.FINDINGS: The mean age of the patients was 42.8±12.4. 30.8% (8 cases) of population were men and 69.2% (18 cases) were women. Fourth, fifth and sixth decades were the most commonly affected decades. 46.2% (12) of patients had systemic disease and 3 (11.5%) of patients had a skin lesion. Fourteen (53.8%) of patients use drug for systemic disease. Nineteen (73%) of patients reported exact time for duration of lesions. The most common affected area was buccal mucosa and the most common lesion that reported was reticular type. Four (15.4%) of patients showed dysplasia on their oral lesions.CONCLUSION: Due to higher incidence of oral lichenoid lesions in 30 year old to 60 year old women, clinical examination of oral mucosa must be considered in middle aged women. Also considerable percentage of dysplastic changes in oral lichenoid lesions reveals that these patients must be followed up.
format article
author M Seyedmajidi
M Motallebnejad
R Foroughi,
F Aslani
author_facet M Seyedmajidi
M Motallebnejad
R Foroughi,
F Aslani
author_sort M Seyedmajidi
title Clinical and Histopathological Findings in 26 Patients with Oral Lichenoid Lesions
title_short Clinical and Histopathological Findings in 26 Patients with Oral Lichenoid Lesions
title_full Clinical and Histopathological Findings in 26 Patients with Oral Lichenoid Lesions
title_fullStr Clinical and Histopathological Findings in 26 Patients with Oral Lichenoid Lesions
title_full_unstemmed Clinical and Histopathological Findings in 26 Patients with Oral Lichenoid Lesions
title_sort clinical and histopathological findings in 26 patients with oral lichenoid lesions
publisher Babol University of Medical Sciences
publishDate 2010
url https://doaj.org/article/93f04c585e9e41a4a16ccc8f12105fcd
work_keys_str_mv AT mseyedmajidi clinicalandhistopathologicalfindingsin26patientswithorallichenoidlesions
AT mmotallebnejad clinicalandhistopathologicalfindingsin26patientswithorallichenoidlesions
AT rforoughi clinicalandhistopathologicalfindingsin26patientswithorallichenoidlesions
AT faslani clinicalandhistopathologicalfindingsin26patientswithorallichenoidlesions
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