Volumetric breast density estimation from full-field digital mammograms: a validation study.
<h4>Objectives</h4>To objectively evaluate automatic volumetric breast density assessment in Full-Field Digital Mammograms (FFDM) using measurements obtained from breast Magnetic Resonance Imaging (MRI).<h4>Material and methods</h4>A commercially available method for volumetr...
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2014
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oai:doaj.org-article:93fb37c575cc413caef60e8bf73800c72021-11-18T08:36:54ZVolumetric breast density estimation from full-field digital mammograms: a validation study.1932-620310.1371/journal.pone.0085952https://doaj.org/article/93fb37c575cc413caef60e8bf73800c72014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24465808/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Objectives</h4>To objectively evaluate automatic volumetric breast density assessment in Full-Field Digital Mammograms (FFDM) using measurements obtained from breast Magnetic Resonance Imaging (MRI).<h4>Material and methods</h4>A commercially available method for volumetric breast density estimation on FFDM is evaluated by comparing volume estimates obtained from 186 FFDM exams including mediolateral oblique (MLO) and cranial-caudal (CC) views to objective reference standard measurements obtained from MRI.<h4>Results</h4>Volumetric measurements obtained from FFDM show high correlation with MRI data. Pearson's correlation coefficients of 0.93, 0.97 and 0.85 were obtained for volumetric breast density, breast volume and fibroglandular tissue volume, respectively.<h4>Conclusions</h4>Accurate volumetric breast density assessment is feasible in Full-Field Digital Mammograms and has potential to be used in objective breast cancer risk models and personalized screening.Albert Gubern-MéridaMichiel KallenbergBram PlatelRitse M MannRobert MartíNico KarssemeijerPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 1, p e85952 (2014) |
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Medicine R Science Q Albert Gubern-Mérida Michiel Kallenberg Bram Platel Ritse M Mann Robert Martí Nico Karssemeijer Volumetric breast density estimation from full-field digital mammograms: a validation study. |
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<h4>Objectives</h4>To objectively evaluate automatic volumetric breast density assessment in Full-Field Digital Mammograms (FFDM) using measurements obtained from breast Magnetic Resonance Imaging (MRI).<h4>Material and methods</h4>A commercially available method for volumetric breast density estimation on FFDM is evaluated by comparing volume estimates obtained from 186 FFDM exams including mediolateral oblique (MLO) and cranial-caudal (CC) views to objective reference standard measurements obtained from MRI.<h4>Results</h4>Volumetric measurements obtained from FFDM show high correlation with MRI data. Pearson's correlation coefficients of 0.93, 0.97 and 0.85 were obtained for volumetric breast density, breast volume and fibroglandular tissue volume, respectively.<h4>Conclusions</h4>Accurate volumetric breast density assessment is feasible in Full-Field Digital Mammograms and has potential to be used in objective breast cancer risk models and personalized screening. |
format |
article |
author |
Albert Gubern-Mérida Michiel Kallenberg Bram Platel Ritse M Mann Robert Martí Nico Karssemeijer |
author_facet |
Albert Gubern-Mérida Michiel Kallenberg Bram Platel Ritse M Mann Robert Martí Nico Karssemeijer |
author_sort |
Albert Gubern-Mérida |
title |
Volumetric breast density estimation from full-field digital mammograms: a validation study. |
title_short |
Volumetric breast density estimation from full-field digital mammograms: a validation study. |
title_full |
Volumetric breast density estimation from full-field digital mammograms: a validation study. |
title_fullStr |
Volumetric breast density estimation from full-field digital mammograms: a validation study. |
title_full_unstemmed |
Volumetric breast density estimation from full-field digital mammograms: a validation study. |
title_sort |
volumetric breast density estimation from full-field digital mammograms: a validation study. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2014 |
url |
https://doaj.org/article/93fb37c575cc413caef60e8bf73800c7 |
work_keys_str_mv |
AT albertgubernmerida volumetricbreastdensityestimationfromfullfielddigitalmammogramsavalidationstudy AT michielkallenberg volumetricbreastdensityestimationfromfullfielddigitalmammogramsavalidationstudy AT bramplatel volumetricbreastdensityestimationfromfullfielddigitalmammogramsavalidationstudy AT ritsemmann volumetricbreastdensityestimationfromfullfielddigitalmammogramsavalidationstudy AT robertmarti volumetricbreastdensityestimationfromfullfielddigitalmammogramsavalidationstudy AT nicokarssemeijer volumetricbreastdensityestimationfromfullfielddigitalmammogramsavalidationstudy |
_version_ |
1718421574606913536 |