Conserved presence of G-quadruplex forming sequences in the Long Terminal Repeat Promoter of Lentiviruses
Abstract G-quadruplexes (G4s) are secondary structures of nucleic acids that epigenetically regulate cellular processes. In the human immunodeficiency lentivirus 1 (HIV-1), dynamic G4s are located in the unique viral LTR promoter. Folding of HIV-1 LTR G4s inhibits viral transcription; stabilization...
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| Auteurs principaux: | , , , |
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| Format: | article |
| Langue: | EN |
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Nature Portfolio
2017
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| Accès en ligne: | https://doaj.org/article/93fd701a8a2743ff8827e3e7d8a9ac41 |
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