A plasma membrane microdomain compartmentalizes ephrin-generated cAMP signals to prune developing retinal axon arbors
It is unclear what role cholesterol-enriched domains of the plasma membrane play in mediating the development of neuronal circuits. Here, the authors show that such domains localize ephrin-A-induced cAMP signals, causing the pruning of retinal ganglion cell axons.
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| Autores principales: | , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2016
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/94050756e0ed422e8dfa1ae1650db453 |
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