Bone marrow mesenchymal stem cells for improving hematopoietic function: an in vitro and in vivo model. Part 2: Effect on bone marrow microenvironment.

Bone marrow mesenchymal stem cells for improving hematopoietic function: an in vitro and in vivo model. Part 2: Effect on bone marrow microenvironment.

The aim of the present study was to determine how mesenchymal stem cells (MSC) could improve bone marrow (BM) stroma function after damage, both in vitro and in vivo. Human MSC from 20 healthy donors were isolated and expanded. Mobilized selected CD34(+) progenitor cells were obtained from 20 HSCT d...

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Bibliographic Details
Main Authors: Soraya Carrancio, Belen Blanco, Carlos Romo, Sandra Muntion, Natalia Lopez-Holgado, Juan F Blanco, Jesus G Briñon, Jesus F San Miguel, Fermin M Sanchez-Guijo, M Consuelo del Cañizo
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/94060712a0bd4b4c84244f9b24e76e42
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