Potential Microbiological Risk Factors Associated With Periodontitis and Periodontal Health Disparities

Periodontitis disproportionately affects different racial and ethnic populations. In this study, we used qPCR to determine and compare oral microbial profiles in dental plaque samples from 191 periodontitis patients of different ethnic/racial backgrounds. We also obtained the periodontal parameters...

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Autores principales:	Bing-Yan Wang, Tom Lu, Qiuyin Cai, Meng-Hsuan Ho, Sally Sheng, Hsiu-Wan Meng, Laura Arsto, Jianming Hong, Hua Xie
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	Porphyromonas gingivalis periodontitis racial and ethnic groups Streptococcus cristatus microbial profiles Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/940959c0bbb24e50acad281cfc84c307
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spelling	oai:doaj.org-article:940959c0bbb24e50acad281cfc84c3072021-11-17T05:49:14ZPotential Microbiological Risk Factors Associated With Periodontitis and Periodontal Health Disparities2235-298810.3389/fcimb.2021.789919https://doaj.org/article/940959c0bbb24e50acad281cfc84c3072021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fcimb.2021.789919/fullhttps://doaj.org/toc/2235-2988Periodontitis disproportionately affects different racial and ethnic populations. In this study, we used qPCR to determine and compare oral microbial profiles in dental plaque samples from 191 periodontitis patients of different ethnic/racial backgrounds. We also obtained the periodontal parameters of these patients retrospectively using axiUm and performed statistical analysis using SAS 9.4. We found that in this patient cohort, neighborhood median incomes were significantly higher among Caucasians Americans (CAs) than among African Americans (AAs) and Hispanic Americans (HAs). Levels of total bacteria and Porphyromonas gingivalis, a keystone periodontal pathogen, were not evenly distributed among the three groups. We confirmed our previous findings that Streptococcus cristatus reduces P. gingivalis virulence potential and likely serves as a beneficial bacterium. We also showed the ratio of S. cristatus to P. gingivalis to be significantly higher in CAs than in HAs and AAs. Our results suggest that higher levels of P. gingivalis and lower ratios of S. cristatus to P. gingivalis may contribute to periodontal health disparities.Bing-Yan WangTom LuQiuyin CaiMeng-Hsuan HoSally ShengHsiu-Wan MengLaura ArstoJianming HongHua XieFrontiers Media S.A.articlePorphyromonas gingivalisperiodontitisracial and ethnic groupsStreptococcus cristatusmicrobial profilesMicrobiologyQR1-502ENFrontiers in Cellular and Infection Microbiology, Vol 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Porphyromonas gingivalis periodontitis racial and ethnic groups Streptococcus cristatus microbial profiles Microbiology QR1-502
spellingShingle	Porphyromonas gingivalis periodontitis racial and ethnic groups Streptococcus cristatus microbial profiles Microbiology QR1-502 Bing-Yan Wang Tom Lu Qiuyin Cai Meng-Hsuan Ho Sally Sheng Hsiu-Wan Meng Laura Arsto Jianming Hong Hua Xie Potential Microbiological Risk Factors Associated With Periodontitis and Periodontal Health Disparities
description	Periodontitis disproportionately affects different racial and ethnic populations. In this study, we used qPCR to determine and compare oral microbial profiles in dental plaque samples from 191 periodontitis patients of different ethnic/racial backgrounds. We also obtained the periodontal parameters of these patients retrospectively using axiUm and performed statistical analysis using SAS 9.4. We found that in this patient cohort, neighborhood median incomes were significantly higher among Caucasians Americans (CAs) than among African Americans (AAs) and Hispanic Americans (HAs). Levels of total bacteria and Porphyromonas gingivalis, a keystone periodontal pathogen, were not evenly distributed among the three groups. We confirmed our previous findings that Streptococcus cristatus reduces P. gingivalis virulence potential and likely serves as a beneficial bacterium. We also showed the ratio of S. cristatus to P. gingivalis to be significantly higher in CAs than in HAs and AAs. Our results suggest that higher levels of P. gingivalis and lower ratios of S. cristatus to P. gingivalis may contribute to periodontal health disparities.
format	article
author	Bing-Yan Wang Tom Lu Qiuyin Cai Meng-Hsuan Ho Sally Sheng Hsiu-Wan Meng Laura Arsto Jianming Hong Hua Xie
author_facet	Bing-Yan Wang Tom Lu Qiuyin Cai Meng-Hsuan Ho Sally Sheng Hsiu-Wan Meng Laura Arsto Jianming Hong Hua Xie
author_sort	Bing-Yan Wang
title	Potential Microbiological Risk Factors Associated With Periodontitis and Periodontal Health Disparities
title_short	Potential Microbiological Risk Factors Associated With Periodontitis and Periodontal Health Disparities
title_full	Potential Microbiological Risk Factors Associated With Periodontitis and Periodontal Health Disparities
title_fullStr	Potential Microbiological Risk Factors Associated With Periodontitis and Periodontal Health Disparities
title_full_unstemmed	Potential Microbiological Risk Factors Associated With Periodontitis and Periodontal Health Disparities
title_sort	potential microbiological risk factors associated with periodontitis and periodontal health disparities
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/940959c0bbb24e50acad281cfc84c307
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Potential Microbiological Risk Factors Associated With Periodontitis and Periodontal Health Disparities

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