Single cell analysis of lymph node tissue from HIV-1 infected patients reveals that the majority of CD4+ T-cells contain one HIV-1 DNA molecule.

Single cell analysis of lymph node tissue from HIV-1 infected patients reveals that the majority of CD4+ T-cells contain one HIV-1 DNA molecule.

Genetic recombination contributes to the diversity of human immunodeficiency virus (HIV-1). Productive HIV-1 recombination is, however, dependent on both the number of HIV-1 genomes per infected cell and the genetic relationship between these viral genomes. A detailed analysis of the number of provi...

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Autores principales: Lina Josefsson, Sarah Palmer, Nuno R Faria, Philippe Lemey, Joseph Casazza, David Ambrozak, Mary Kearney, Wei Shao, Shyamasundaran Kottilil, Michael Sneller, John Mellors, John M Coffin, Frank Maldarelli
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/940b3bbf102643bc9774ff04f63b1984
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