Autofluorescence as a noninvasive biomarker of senescence and advanced glycation end products in Caenorhabditis elegans

Abstract To assess the utility of autofluorescence as a noninvasive biomarker of senescence in Caenorhabditis elegans, we measured the autofluorescence of individual nematodes using spectrofluorometry. The fluorescence of each worm increased with age. Animals with lower fluorescence intensity exhibi...

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Bibliographic Details
Main Authors: Tomomi Komura, Mikihiro Yamanaka, Kohji Nishimura, Keita Hara, Yoshikazu Nishikawa
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/940c30c7908e44b69bc4ef3ed9ecd63a
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