Cell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression
Quantifying the propagation of mechanical stress in multicellular tissues remains challenging. Here the authors develop polyacrylamide microbeads as sensors that accurately report on stress within spheroids and show that external compression results in a rise in pressure towards the core.
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| Autores principales: | , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2017
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/94118a2bcac0454db8f00dd6b448abf3 |
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| Sumario: | Quantifying the propagation of mechanical stress in multicellular tissues remains challenging. Here the authors develop polyacrylamide microbeads as sensors that accurately report on stress within spheroids and show that external compression results in a rise in pressure towards the core. |
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