Cell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression

Quantifying the propagation of mechanical stress in multicellular tissues remains challenging. Here the authors develop polyacrylamide microbeads as sensors that accurately report on stress within spheroids and show that external compression results in a rise in pressure towards the core.

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Autores principales:	M. E. Dolega, M. Delarue, F. Ingremeau, J. Prost, A. Delon, G. Cappello
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/94118a2bcac0454db8f00dd6b448abf3
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spelling	oai:doaj.org-article:94118a2bcac0454db8f00dd6b448abf32021-12-02T17:06:08ZCell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression10.1038/ncomms140562041-1723https://doaj.org/article/94118a2bcac0454db8f00dd6b448abf32017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14056https://doaj.org/toc/2041-1723Quantifying the propagation of mechanical stress in multicellular tissues remains challenging. Here the authors develop polyacrylamide microbeads as sensors that accurately report on stress within spheroids and show that external compression results in a rise in pressure towards the core.M. E. DolegaM. DelarueF. IngremeauJ. ProstA. DelonG. CappelloNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q M. E. Dolega M. Delarue F. Ingremeau J. Prost A. Delon G. Cappello Cell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression
description	Quantifying the propagation of mechanical stress in multicellular tissues remains challenging. Here the authors develop polyacrylamide microbeads as sensors that accurately report on stress within spheroids and show that external compression results in a rise in pressure towards the core.
format	article
author	M. E. Dolega M. Delarue F. Ingremeau J. Prost A. Delon G. Cappello
author_facet	M. E. Dolega M. Delarue F. Ingremeau J. Prost A. Delon G. Cappello
author_sort	M. E. Dolega
title	Cell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression
title_short	Cell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression
title_full	Cell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression
title_fullStr	Cell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression
title_full_unstemmed	Cell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression
title_sort	cell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/94118a2bcac0454db8f00dd6b448abf3
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Cell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression

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