Hyperkalaemia in Heart Failure
Hyperkalaemia has become an increasingly prevalent finding in patients with heart failure (HF), especially with renin–angiotensin–aldosterone system (RAAS) inhibitors and angiotensin–neprilysin inhibitors being the cornerstone of medical therapy. Patients living with HF often have other comorbiditie...
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Radcliffe Medical Media
2021
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oai:doaj.org-article:9419a0cd11214729a55fb865490794832021-12-04T16:04:27ZHyperkalaemia in Heart Failure10.15420/cfr.2020.292057-75592057-7540https://doaj.org/article/9419a0cd11214729a55fb865490794832021-05-01T00:00:00Zhttps://www.cfrjournal.com/articleindex/cfr.2020.29https://doaj.org/toc/2057-7540https://doaj.org/toc/2057-7559Hyperkalaemia has become an increasingly prevalent finding in patients with heart failure (HF), especially with renin–angiotensin–aldosterone system (RAAS) inhibitors and angiotensin–neprilysin inhibitors being the cornerstone of medical therapy. Patients living with HF often have other comorbidities, such as diabetes and chronic kidney disease, which predispose to hyperkalaemia. Until now, we have not had any reliable or tolerable therapies for the treatment of hyperkalaemia to facilitate implementation or achievement of target doses of RAAS inhibition. Patiromer sorbitex calcium and sodium zirconium cyclosilicate are two novel potassium-binding resins that have shown promise in the management of patients predisposed to developing recurrent hyperkalaemia, and their use may allow for further optimisation of guideline directed medical therapy.Umar IsmailKiran SidhuShelley ZierothRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENCardiac Failure Review , Vol 7, Iss , Pp - (2021) |
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Diseases of the circulatory (Cardiovascular) system RC666-701 |
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Diseases of the circulatory (Cardiovascular) system RC666-701 Umar Ismail Kiran Sidhu Shelley Zieroth Hyperkalaemia in Heart Failure |
description |
Hyperkalaemia has become an increasingly prevalent finding in patients with heart failure (HF), especially with renin–angiotensin–aldosterone system (RAAS) inhibitors and angiotensin–neprilysin inhibitors being the cornerstone of medical therapy. Patients living with HF often have other comorbidities, such as diabetes and chronic kidney disease, which predispose to hyperkalaemia. Until now, we have not had any reliable or tolerable therapies for the treatment of hyperkalaemia to facilitate implementation or achievement of target doses of RAAS inhibition. Patiromer sorbitex calcium and sodium zirconium cyclosilicate are two novel potassium-binding resins that have shown promise in the management of patients predisposed to developing recurrent hyperkalaemia, and their use may allow for further optimisation of guideline directed medical therapy. |
format |
article |
author |
Umar Ismail Kiran Sidhu Shelley Zieroth |
author_facet |
Umar Ismail Kiran Sidhu Shelley Zieroth |
author_sort |
Umar Ismail |
title |
Hyperkalaemia in Heart Failure |
title_short |
Hyperkalaemia in Heart Failure |
title_full |
Hyperkalaemia in Heart Failure |
title_fullStr |
Hyperkalaemia in Heart Failure |
title_full_unstemmed |
Hyperkalaemia in Heart Failure |
title_sort |
hyperkalaemia in heart failure |
publisher |
Radcliffe Medical Media |
publishDate |
2021 |
url |
https://doaj.org/article/9419a0cd11214729a55fb86549079483 |
work_keys_str_mv |
AT umarismail hyperkalaemiainheartfailure AT kiransidhu hyperkalaemiainheartfailure AT shelleyzieroth hyperkalaemiainheartfailure |
_version_ |
1718372687530688512 |