Hyperkalaemia in Heart Failure

Hyperkalaemia has become an increasingly prevalent finding in patients with heart failure (HF), especially with renin–angiotensin–aldosterone system (RAAS) inhibitors and angiotensin–neprilysin inhibitors being the cornerstone of medical therapy. Patients living with HF often have other comorbiditie...

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Autores principales: Umar Ismail, Kiran Sidhu, Shelley Zieroth
Formato: article
Lenguaje:EN
Publicado: Radcliffe Medical Media 2021
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Acceso en línea:https://doaj.org/article/9419a0cd11214729a55fb86549079483
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spelling oai:doaj.org-article:9419a0cd11214729a55fb865490794832021-12-04T16:04:27ZHyperkalaemia in Heart Failure10.15420/cfr.2020.292057-75592057-7540https://doaj.org/article/9419a0cd11214729a55fb865490794832021-05-01T00:00:00Zhttps://www.cfrjournal.com/articleindex/cfr.2020.29https://doaj.org/toc/2057-7540https://doaj.org/toc/2057-7559Hyperkalaemia has become an increasingly prevalent finding in patients with heart failure (HF), especially with renin–angiotensin–aldosterone system (RAAS) inhibitors and angiotensin–neprilysin inhibitors being the cornerstone of medical therapy. Patients living with HF often have other comorbidities, such as diabetes and chronic kidney disease, which predispose to hyperkalaemia. Until now, we have not had any reliable or tolerable therapies for the treatment of hyperkalaemia to facilitate implementation or achievement of target doses of RAAS inhibition. Patiromer sorbitex calcium and sodium zirconium cyclosilicate are two novel potassium-binding resins that have shown promise in the management of patients predisposed to developing recurrent hyperkalaemia, and their use may allow for further optimisation of guideline directed medical therapy.Umar IsmailKiran SidhuShelley ZierothRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENCardiac Failure Review , Vol 7, Iss , Pp - (2021)
institution DOAJ
collection DOAJ
language EN
topic Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle Diseases of the circulatory (Cardiovascular) system
RC666-701
Umar Ismail
Kiran Sidhu
Shelley Zieroth
Hyperkalaemia in Heart Failure
description Hyperkalaemia has become an increasingly prevalent finding in patients with heart failure (HF), especially with renin–angiotensin–aldosterone system (RAAS) inhibitors and angiotensin–neprilysin inhibitors being the cornerstone of medical therapy. Patients living with HF often have other comorbidities, such as diabetes and chronic kidney disease, which predispose to hyperkalaemia. Until now, we have not had any reliable or tolerable therapies for the treatment of hyperkalaemia to facilitate implementation or achievement of target doses of RAAS inhibition. Patiromer sorbitex calcium and sodium zirconium cyclosilicate are two novel potassium-binding resins that have shown promise in the management of patients predisposed to developing recurrent hyperkalaemia, and their use may allow for further optimisation of guideline directed medical therapy.
format article
author Umar Ismail
Kiran Sidhu
Shelley Zieroth
author_facet Umar Ismail
Kiran Sidhu
Shelley Zieroth
author_sort Umar Ismail
title Hyperkalaemia in Heart Failure
title_short Hyperkalaemia in Heart Failure
title_full Hyperkalaemia in Heart Failure
title_fullStr Hyperkalaemia in Heart Failure
title_full_unstemmed Hyperkalaemia in Heart Failure
title_sort hyperkalaemia in heart failure
publisher Radcliffe Medical Media
publishDate 2021
url https://doaj.org/article/9419a0cd11214729a55fb86549079483
work_keys_str_mv AT umarismail hyperkalaemiainheartfailure
AT kiransidhu hyperkalaemiainheartfailure
AT shelleyzieroth hyperkalaemiainheartfailure
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