In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation
It is unclear how the T-tubule structure of skeletal muscle, which regulates coordinated muscle contraction, forms. Here, the authors develop a four-dimensional quantitative model for T-tubule formation in zebrafish, based on live imaging, proposing a dynamic endocytic capture model.
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Nature Portfolio
2020
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oai:doaj.org-article:941cb3d60f0f45e1a240d47b1985557b2021-12-02T16:18:02ZIn vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation10.1038/s41467-020-17486-w2041-1723https://doaj.org/article/941cb3d60f0f45e1a240d47b1985557b2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17486-whttps://doaj.org/toc/2041-1723It is unclear how the T-tubule structure of skeletal muscle, which regulates coordinated muscle contraction, forms. Here, the authors develop a four-dimensional quantitative model for T-tubule formation in zebrafish, based on live imaging, proposing a dynamic endocytic capture model.Thomas E. HallNick MartelNicholas AriottiZherui XiongHarriet P. LoCharles FergusonJames RaeYe-Wheen LimRobert G. PartonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-19 (2020) |
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Science Q Thomas E. Hall Nick Martel Nicholas Ariotti Zherui Xiong Harriet P. Lo Charles Ferguson James Rae Ye-Wheen Lim Robert G. Parton In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation |
description |
It is unclear how the T-tubule structure of skeletal muscle, which regulates coordinated muscle contraction, forms. Here, the authors develop a four-dimensional quantitative model for T-tubule formation in zebrafish, based on live imaging, proposing a dynamic endocytic capture model. |
format |
article |
author |
Thomas E. Hall Nick Martel Nicholas Ariotti Zherui Xiong Harriet P. Lo Charles Ferguson James Rae Ye-Wheen Lim Robert G. Parton |
author_facet |
Thomas E. Hall Nick Martel Nicholas Ariotti Zherui Xiong Harriet P. Lo Charles Ferguson James Rae Ye-Wheen Lim Robert G. Parton |
author_sort |
Thomas E. Hall |
title |
In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation |
title_short |
In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation |
title_full |
In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation |
title_fullStr |
In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation |
title_full_unstemmed |
In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation |
title_sort |
in vivo cell biological screening identifies an endocytic capture mechanism for t-tubule formation |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/941cb3d60f0f45e1a240d47b1985557b |
work_keys_str_mv |
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1718384244608204800 |