In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation

It is unclear how the T-tubule structure of skeletal muscle, which regulates coordinated muscle contraction, forms. Here, the authors develop a four-dimensional quantitative model for T-tubule formation in zebrafish, based on live imaging, proposing a dynamic endocytic capture model.

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Autores principales: Thomas E. Hall, Nick Martel, Nicholas Ariotti, Zherui Xiong, Harriet P. Lo, Charles Ferguson, James Rae, Ye-Wheen Lim, Robert G. Parton
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/941cb3d60f0f45e1a240d47b1985557b
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spelling oai:doaj.org-article:941cb3d60f0f45e1a240d47b1985557b2021-12-02T16:18:02ZIn vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation10.1038/s41467-020-17486-w2041-1723https://doaj.org/article/941cb3d60f0f45e1a240d47b1985557b2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17486-whttps://doaj.org/toc/2041-1723It is unclear how the T-tubule structure of skeletal muscle, which regulates coordinated muscle contraction, forms. Here, the authors develop a four-dimensional quantitative model for T-tubule formation in zebrafish, based on live imaging, proposing a dynamic endocytic capture model.Thomas E. HallNick MartelNicholas AriottiZherui XiongHarriet P. LoCharles FergusonJames RaeYe-Wheen LimRobert G. PartonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Thomas E. Hall
Nick Martel
Nicholas Ariotti
Zherui Xiong
Harriet P. Lo
Charles Ferguson
James Rae
Ye-Wheen Lim
Robert G. Parton
In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation
description It is unclear how the T-tubule structure of skeletal muscle, which regulates coordinated muscle contraction, forms. Here, the authors develop a four-dimensional quantitative model for T-tubule formation in zebrafish, based on live imaging, proposing a dynamic endocytic capture model.
format article
author Thomas E. Hall
Nick Martel
Nicholas Ariotti
Zherui Xiong
Harriet P. Lo
Charles Ferguson
James Rae
Ye-Wheen Lim
Robert G. Parton
author_facet Thomas E. Hall
Nick Martel
Nicholas Ariotti
Zherui Xiong
Harriet P. Lo
Charles Ferguson
James Rae
Ye-Wheen Lim
Robert G. Parton
author_sort Thomas E. Hall
title In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation
title_short In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation
title_full In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation
title_fullStr In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation
title_full_unstemmed In vivo cell biological screening identifies an endocytic capture mechanism for T-tubule formation
title_sort in vivo cell biological screening identifies an endocytic capture mechanism for t-tubule formation
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/941cb3d60f0f45e1a240d47b1985557b
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