Clinical features and treatment of maturity onset diabetes of the young (MODY)

Daphne SL Gardner1, E Shyong Tai21Department of Endocrinology, Singapore General Hospital, 2Department of Endocrinology, National University Hospital, SingaporeAbstract: Maturity onset diabetes of the young (MODY) is a heterogeneous group of disorders that result in ß-cell dysfunction....

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Main Author: Gardner DS,Tai ES
Format: article
Language:EN
Published: Dove Medical Press 2012
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Online Access:https://doaj.org/article/9423ff8a77d044c99d2c2c69f6f7aec3
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spelling oai:doaj.org-article:9423ff8a77d044c99d2c2c69f6f7aec32021-12-02T04:43:25ZClinical features and treatment of maturity onset diabetes of the young (MODY)1178-7007https://doaj.org/article/9423ff8a77d044c99d2c2c69f6f7aec32012-05-01T00:00:00Zhttp://www.dovepress.com/clinical-features-and-treatment-of-maturity-onset-diabetes-of-the-youn-a9796https://doaj.org/toc/1178-7007Daphne SL Gardner1, E Shyong Tai21Department of Endocrinology, Singapore General Hospital, 2Department of Endocrinology, National University Hospital, SingaporeAbstract: Maturity onset diabetes of the young (MODY) is a heterogeneous group of disorders that result in ß-cell dysfunction. It is rare, accounting for just 1%–2% of all diabetes. It is often misdiagnosed as type 1 or type 2 diabetes, as it is often difficult to distinguish MODY from these two forms. However, diagnosis allows appropriate individualized care, depending on the genetic etiology, and allows prognostication in family members. In this review, we discuss features of the common causes of MODY, as well as the treatment and diagnosis of MODY.Keywords: type 1 diabetes, type 2 diabetes, HNF1A, HNF4A, HNF1B, GCKGardner DS,Tai ESDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2012, Iss default, Pp 101-108 (2012)
institution DOAJ
collection DOAJ
language EN
topic Specialties of internal medicine
RC581-951
spellingShingle Specialties of internal medicine
RC581-951
Gardner DS,Tai ES
Clinical features and treatment of maturity onset diabetes of the young (MODY)
description Daphne SL Gardner1, E Shyong Tai21Department of Endocrinology, Singapore General Hospital, 2Department of Endocrinology, National University Hospital, SingaporeAbstract: Maturity onset diabetes of the young (MODY) is a heterogeneous group of disorders that result in ß-cell dysfunction. It is rare, accounting for just 1%–2% of all diabetes. It is often misdiagnosed as type 1 or type 2 diabetes, as it is often difficult to distinguish MODY from these two forms. However, diagnosis allows appropriate individualized care, depending on the genetic etiology, and allows prognostication in family members. In this review, we discuss features of the common causes of MODY, as well as the treatment and diagnosis of MODY.Keywords: type 1 diabetes, type 2 diabetes, HNF1A, HNF4A, HNF1B, GCK
format article
author Gardner DS,Tai ES
author_facet Gardner DS,Tai ES
author_sort Gardner DS,Tai ES
title Clinical features and treatment of maturity onset diabetes of the young (MODY)
title_short Clinical features and treatment of maturity onset diabetes of the young (MODY)
title_full Clinical features and treatment of maturity onset diabetes of the young (MODY)
title_fullStr Clinical features and treatment of maturity onset diabetes of the young (MODY)
title_full_unstemmed Clinical features and treatment of maturity onset diabetes of the young (MODY)
title_sort clinical features and treatment of maturity onset diabetes of the young (mody)
publisher Dove Medical Press
publishDate 2012
url https://doaj.org/article/9423ff8a77d044c99d2c2c69f6f7aec3
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