Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation

Memory T cells are vital responders to skin inflammation, but cell localization and dynamics of exchange with the bloodstream are not clear. Here the authors use parabiosis and intravital microscopy to show that CD4+memory T cells equilibrate with the circulation and cluster around hair follicles in...

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Auteurs principaux: Nicholas Collins, Xiaodong Jiang, Ali Zaid, Bethany L. Macleod, Jane Li, Chang Ook Park, Ashraful Haque, Sammy Bedoui, William R. Heath, Scott N. Mueller, Thomas S. Kupper, Thomas Gebhardt, Francis R. Carbone
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/9429c534091c48ec9b67d0bb26d4ecdf
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