Caenorhabditis elegans N-glycan core beta-galactoside confers sensitivity towards nematotoxic fungal galectin CGL2.
The physiological role of fungal galectins has remained elusive. Here, we show that feeding of a mushroom galectin, Coprinopsis cinerea CGL2, to Caenorhabditis elegans inhibited development and reproduction and ultimately resulted in killing of this nematode. The lack of toxicity of a carbohydrate-b...
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Autores principales: | Alex Butschi, Alexander Titz, Martin A Wälti, Vincent Olieric, Katharina Paschinger, Katharina Nöbauer, Xiaoqiang Guo, Peter H Seeberger, Iain B H Wilson, Markus Aebi, Michael O Hengartner, Markus Künzler |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
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Materias: | |
Acceso en línea: | https://doaj.org/article/9436674aad2740f085e0ecbf4461a06c |
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