Hierarchical differentiation of myeloid progenitors is encoded in the transcription factor network.

Hematopoiesis is an ideal model system for stem cell biology with advanced experimental access. A systems view on the interactions of core transcription factors is important for understanding differentiation mechanisms and dynamics. In this manuscript, we construct a Boolean network to model myeloid...

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Auteurs principaux: Jan Krumsiek, Carsten Marr, Timm Schroeder, Fabian J Theis
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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R
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Accès en ligne:https://doaj.org/article/944146055e3b4ec4b2fd7bdd7efb2555
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