Hierarchical differentiation of myeloid progenitors is encoded in the transcription factor network.
Hematopoiesis is an ideal model system for stem cell biology with advanced experimental access. A systems view on the interactions of core transcription factors is important for understanding differentiation mechanisms and dynamics. In this manuscript, we construct a Boolean network to model myeloid...
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Autores principales: | Jan Krumsiek, Carsten Marr, Timm Schroeder, Fabian J Theis |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/944146055e3b4ec4b2fd7bdd7efb2555 |
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