Medication-related hospital readmissions within 30 days of discharge-A retrospective study of risk factors in older adults.

<h4>Background</h4>Previous studies have shown that approximately 20% of hospital readmissions can be medication-related and 70% of these readmissions are possibly preventable. This retrospective medical records study aimed to find risk factors associated with medication-related readmiss...

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Autores principales:	Maria Glans, Annika Kragh Ekstam, Ulf Jakobsson, Åsa Bondesson, Patrik Midlöv
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/944b7ef08f1e4a27906d6a310c291e9b
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spelling	oai:doaj.org-article:944b7ef08f1e4a27906d6a310c291e9b2021-12-02T20:10:49ZMedication-related hospital readmissions within 30 days of discharge-A retrospective study of risk factors in older adults.1932-620310.1371/journal.pone.0253024https://doaj.org/article/944b7ef08f1e4a27906d6a310c291e9b2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0253024https://doaj.org/toc/1932-6203<h4>Background</h4>Previous studies have shown that approximately 20% of hospital readmissions can be medication-related and 70% of these readmissions are possibly preventable. This retrospective medical records study aimed to find risk factors associated with medication-related readmissions to hospital within 30 days of discharge in older adults (≥65 years).<h4>Methods</h4>30-day readmissions (n = 360) were assessed as being either possibly or unlikely medication-related after which selected variables were used to individually compare the two groups to a comparison group (n = 360). The aim was to find individual risk factors of possibly medication-related readmissions focusing on living arrangements, polypharmacy, potentially inappropriate medication therapy, and changes made to medication regimens at initial discharge.<h4>Results</h4>A total of 143 of the 360 readmissions (40%) were assessed as being possibly medication-related. Charlson Comorbidity Index (OR 1.15, 95%CI 1.5-1.25), excessive polypharmacy (OR 1.74, 95%CI 1.07-2.81), having adjustments made to medication dosages at initial discharge (OR 1.63, 95%CI 1.03-2.58) and living in your own home, alone, were variables identified as risk factors of such readmissions. Living in your own home, alone, increased the odds of a possibly medication-related readmission 1.69 times compared to living in your own home with someone (p-value 0.025) and 2.22 times compared to living in a nursing home (p-value 0.037).<h4>Conclusion</h4>Possibly medication-related readmissions within 30 days of discharge, in patients 65 years and older, are common. The odds of such readmissions increase in comorbid, highly medicated patients living in their own home, alone, and if having medication dosages adjusted at initial discharge. These results indicate that care planning before discharge and the provision of help with, for example, managing medications after discharge, are factors especially important if aiming to reduce the amount of medication-related readmissions among this population. Further research is needed to confirm this hypothesis.Maria GlansAnnika Kragh EkstamUlf JakobssonÅsa BondessonPatrik MidlövPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0253024 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Maria Glans Annika Kragh Ekstam Ulf Jakobsson Åsa Bondesson Patrik Midlöv Medication-related hospital readmissions within 30 days of discharge-A retrospective study of risk factors in older adults.
description	<h4>Background</h4>Previous studies have shown that approximately 20% of hospital readmissions can be medication-related and 70% of these readmissions are possibly preventable. This retrospective medical records study aimed to find risk factors associated with medication-related readmissions to hospital within 30 days of discharge in older adults (≥65 years).<h4>Methods</h4>30-day readmissions (n = 360) were assessed as being either possibly or unlikely medication-related after which selected variables were used to individually compare the two groups to a comparison group (n = 360). The aim was to find individual risk factors of possibly medication-related readmissions focusing on living arrangements, polypharmacy, potentially inappropriate medication therapy, and changes made to medication regimens at initial discharge.<h4>Results</h4>A total of 143 of the 360 readmissions (40%) were assessed as being possibly medication-related. Charlson Comorbidity Index (OR 1.15, 95%CI 1.5-1.25), excessive polypharmacy (OR 1.74, 95%CI 1.07-2.81), having adjustments made to medication dosages at initial discharge (OR 1.63, 95%CI 1.03-2.58) and living in your own home, alone, were variables identified as risk factors of such readmissions. Living in your own home, alone, increased the odds of a possibly medication-related readmission 1.69 times compared to living in your own home with someone (p-value 0.025) and 2.22 times compared to living in a nursing home (p-value 0.037).<h4>Conclusion</h4>Possibly medication-related readmissions within 30 days of discharge, in patients 65 years and older, are common. The odds of such readmissions increase in comorbid, highly medicated patients living in their own home, alone, and if having medication dosages adjusted at initial discharge. These results indicate that care planning before discharge and the provision of help with, for example, managing medications after discharge, are factors especially important if aiming to reduce the amount of medication-related readmissions among this population. Further research is needed to confirm this hypothesis.
format	article
author	Maria Glans Annika Kragh Ekstam Ulf Jakobsson Åsa Bondesson Patrik Midlöv
author_facet	Maria Glans Annika Kragh Ekstam Ulf Jakobsson Åsa Bondesson Patrik Midlöv
author_sort	Maria Glans
title	Medication-related hospital readmissions within 30 days of discharge-A retrospective study of risk factors in older adults.
title_short	Medication-related hospital readmissions within 30 days of discharge-A retrospective study of risk factors in older adults.
title_full	Medication-related hospital readmissions within 30 days of discharge-A retrospective study of risk factors in older adults.
title_fullStr	Medication-related hospital readmissions within 30 days of discharge-A retrospective study of risk factors in older adults.
title_full_unstemmed	Medication-related hospital readmissions within 30 days of discharge-A retrospective study of risk factors in older adults.
title_sort	medication-related hospital readmissions within 30 days of discharge-a retrospective study of risk factors in older adults.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/944b7ef08f1e4a27906d6a310c291e9b
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Medication-related hospital readmissions within 30 days of discharge-A retrospective study of risk factors in older adults.

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