Integrated molecular characterization reveals potential therapeutic strategies for pulmonary sarcomatoid carcinoma

Pulmonary sarcomatoid carcinoma (PSC) is a rare subtype of lung cancer with poor prognosis. Here the authors performed multi-omics analysis of human samples to investigate the mutational landscape of PSC and show three subgroups of PSC with distinct biology, prognosis and potential therapeutic strat...

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Autores principales: Zhenlin Yang, Jiachen Xu, Lin Li, Renda Li, Yalong Wang, Yanhua Tian, Wei Guo, Zhijie Wang, Fengwei Tan, Jianming Ying, Yuchen Jiao, Shugeng Gao, Jie Wang, Yibo Gao, Jie He
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/9450754d048f4b36a59fec1342fbe22f
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Sumario:Pulmonary sarcomatoid carcinoma (PSC) is a rare subtype of lung cancer with poor prognosis. Here the authors performed multi-omics analysis of human samples to investigate the mutational landscape of PSC and show three subgroups of PSC with distinct biology, prognosis and potential therapeutic strategies.