Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation

Dihydrobenzofurans and indolines are common substructures in medicines and natural products. Herein, the authors report a palladium-catalyzed [3 + 2] (hetero)annulation proceeding in an anti-selective fashion and enabling direct access to these valuable heterocycles with broad reaction scope.

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Autores principales:	Hui-Qi Ni, Ilia Kevlishvili, Pranali G. Bedekar, Joyann S. Barber, Shouliang Yang, Michelle Tran-Dubé, Andrew M. Romine, Hou-Xiang Lu, Indrawan J. McAlpine, Peng Liu, Keary M. Engle
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/945084f36cfa4b7a9ef932ab16789629
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spelling	oai:doaj.org-article:945084f36cfa4b7a9ef932ab167896292021-12-02T13:24:15ZAnti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation10.1038/s41467-020-20182-42041-1723https://doaj.org/article/945084f36cfa4b7a9ef932ab167896292020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20182-4https://doaj.org/toc/2041-1723Dihydrobenzofurans and indolines are common substructures in medicines and natural products. Herein, the authors report a palladium-catalyzed [3 + 2] (hetero)annulation proceeding in an anti-selective fashion and enabling direct access to these valuable heterocycles with broad reaction scope.Hui-Qi NiIlia KevlishviliPranali G. BedekarJoyann S. BarberShouliang YangMichelle Tran-DubéAndrew M. RomineHou-Xiang LuIndrawan J. McAlpinePeng LiuKeary M. EngleNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hui-Qi Ni Ilia Kevlishvili Pranali G. Bedekar Joyann S. Barber Shouliang Yang Michelle Tran-Dubé Andrew M. Romine Hou-Xiang Lu Indrawan J. McAlpine Peng Liu Keary M. Engle Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation
description	Dihydrobenzofurans and indolines are common substructures in medicines and natural products. Herein, the authors report a palladium-catalyzed [3 + 2] (hetero)annulation proceeding in an anti-selective fashion and enabling direct access to these valuable heterocycles with broad reaction scope.
format	article
author	Hui-Qi Ni Ilia Kevlishvili Pranali G. Bedekar Joyann S. Barber Shouliang Yang Michelle Tran-Dubé Andrew M. Romine Hou-Xiang Lu Indrawan J. McAlpine Peng Liu Keary M. Engle
author_facet	Hui-Qi Ni Ilia Kevlishvili Pranali G. Bedekar Joyann S. Barber Shouliang Yang Michelle Tran-Dubé Andrew M. Romine Hou-Xiang Lu Indrawan J. McAlpine Peng Liu Keary M. Engle
author_sort	Hui-Qi Ni
title	Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation
title_short	Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation
title_full	Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation
title_fullStr	Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation
title_full_unstemmed	Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation
title_sort	anti-selective [3+2] (hetero)annulation of non-conjugated alkenes via directed nucleopalladation
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/945084f36cfa4b7a9ef932ab16789629
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Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation

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