Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation

Dihydrobenzofurans and indolines are common substructures in medicines and natural products. Herein, the authors report a palladium-catalyzed [3 + 2] (hetero)annulation proceeding in an anti-selective fashion and enabling direct access to these valuable heterocycles with broad reaction scope.

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Autores principales: Hui-Qi Ni, Ilia Kevlishvili, Pranali G. Bedekar, Joyann S. Barber, Shouliang Yang, Michelle Tran-Dubé, Andrew M. Romine, Hou-Xiang Lu, Indrawan J. McAlpine, Peng Liu, Keary M. Engle
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/945084f36cfa4b7a9ef932ab16789629
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