Nuclear RNA-seq of single neurons reveals molecular signatures of activation

The molecular dynamics associated with neuronal activation patterns in vivo are unclear. Lacar et al. perform single-nuclei RNA-sequencing of hippocampal neurons from mice exposed to a novel environment, and identify large-scale transcriptome changes in individual neurons associated with the experie...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Benjamin Lacar, Sara B. Linker, Baptiste N. Jaeger, Suguna Rani Krishnaswami, Jerika J. Barron, Martijn J. E. Kelder, Sarah L. Parylak, Apuã C. M. Paquola, Pratap Venepally, Mark Novotny, Carolyn O'Connor, Conor Fitzpatrick, Jennifer A. Erwin, Jonathan Y. Hsu, David Husband, Michael J. McConnell, Roger Lasken, Fred H. Gage
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/945908deb567490ab967344cc571a206
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:945908deb567490ab967344cc571a206
record_format	dspace
spelling	oai:doaj.org-article:945908deb567490ab967344cc571a2062021-12-02T14:40:14ZNuclear RNA-seq of single neurons reveals molecular signatures of activation10.1038/ncomms110222041-1723https://doaj.org/article/945908deb567490ab967344cc571a2062016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11022https://doaj.org/toc/2041-1723The molecular dynamics associated with neuronal activation patterns in vivo are unclear. Lacar et al. perform single-nuclei RNA-sequencing of hippocampal neurons from mice exposed to a novel environment, and identify large-scale transcriptome changes in individual neurons associated with the experience.Benjamin LacarSara B. LinkerBaptiste N. JaegerSuguna Rani KrishnaswamiJerika J. BarronMartijn J. E. KelderSarah L. ParylakApuã C. M. PaquolaPratap VenepallyMark NovotnyCarolyn O'ConnorConor FitzpatrickJennifer A. ErwinJonathan Y. HsuDavid HusbandMichael J. McConnellRoger LaskenFred H. GageNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Benjamin Lacar Sara B. Linker Baptiste N. Jaeger Suguna Rani Krishnaswami Jerika J. Barron Martijn J. E. Kelder Sarah L. Parylak Apuã C. M. Paquola Pratap Venepally Mark Novotny Carolyn O'Connor Conor Fitzpatrick Jennifer A. Erwin Jonathan Y. Hsu David Husband Michael J. McConnell Roger Lasken Fred H. Gage Nuclear RNA-seq of single neurons reveals molecular signatures of activation
description	The molecular dynamics associated with neuronal activation patterns in vivo are unclear. Lacar et al. perform single-nuclei RNA-sequencing of hippocampal neurons from mice exposed to a novel environment, and identify large-scale transcriptome changes in individual neurons associated with the experience.
format	article
author	Benjamin Lacar Sara B. Linker Baptiste N. Jaeger Suguna Rani Krishnaswami Jerika J. Barron Martijn J. E. Kelder Sarah L. Parylak Apuã C. M. Paquola Pratap Venepally Mark Novotny Carolyn O'Connor Conor Fitzpatrick Jennifer A. Erwin Jonathan Y. Hsu David Husband Michael J. McConnell Roger Lasken Fred H. Gage
author_facet	Benjamin Lacar Sara B. Linker Baptiste N. Jaeger Suguna Rani Krishnaswami Jerika J. Barron Martijn J. E. Kelder Sarah L. Parylak Apuã C. M. Paquola Pratap Venepally Mark Novotny Carolyn O'Connor Conor Fitzpatrick Jennifer A. Erwin Jonathan Y. Hsu David Husband Michael J. McConnell Roger Lasken Fred H. Gage
author_sort	Benjamin Lacar
title	Nuclear RNA-seq of single neurons reveals molecular signatures of activation
title_short	Nuclear RNA-seq of single neurons reveals molecular signatures of activation
title_full	Nuclear RNA-seq of single neurons reveals molecular signatures of activation
title_fullStr	Nuclear RNA-seq of single neurons reveals molecular signatures of activation
title_full_unstemmed	Nuclear RNA-seq of single neurons reveals molecular signatures of activation
title_sort	nuclear rna-seq of single neurons reveals molecular signatures of activation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/945908deb567490ab967344cc571a206
work_keys_str_mv	AT benjaminlacar nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT sarablinker nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT baptistenjaeger nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT sugunaranikrishnaswami nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT jerikajbarron nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT martijnjekelder nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT sarahlparylak nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT apuacmpaquola nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT pratapvenepally nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT marknovotny nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT carolynoconnor nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT conorfitzpatrick nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT jenniferaerwin nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT jonathanyhsu nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT davidhusband nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT michaeljmcconnell nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT rogerlasken nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation AT fredhgage nuclearrnaseqofsingleneuronsrevealsmolecularsignaturesofactivation
_version_	1718390369273511936

Nuclear RNA-seq of single neurons reveals molecular signatures of activation

Ejemplares similares