Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering

Myosin VI can facilitate the maturation of autophagosomes in autophagy through interactions with Tom1 and autophagy receptors. Here authors report the structure of the cargobinding domain of Myosin VI in complex with Tom1, which provides insights into Myosin IV’s cargo recognition modes.

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Autores principales: Shichen Hu, Yujiao Guo, Yingli Wang, Ying Li, Tao Fu, Zixuan Zhou, Yaru Wang, Jianping Liu, Lifeng Pan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/945bfe09b3fb4db79823e2b763ce2484
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spelling oai:doaj.org-article:945bfe09b3fb4db79823e2b763ce24842021-12-02T16:58:03ZStructure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering10.1038/s41467-019-11481-62041-1723https://doaj.org/article/945bfe09b3fb4db79823e2b763ce24842019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11481-6https://doaj.org/toc/2041-1723Myosin VI can facilitate the maturation of autophagosomes in autophagy through interactions with Tom1 and autophagy receptors. Here authors report the structure of the cargobinding domain of Myosin VI in complex with Tom1, which provides insights into Myosin IV’s cargo recognition modes.Shichen HuYujiao GuoYingli WangYing LiTao FuZixuan ZhouYaru WangJianping LiuLifeng PanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shichen Hu
Yujiao Guo
Yingli Wang
Ying Li
Tao Fu
Zixuan Zhou
Yaru Wang
Jianping Liu
Lifeng Pan
Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering
description Myosin VI can facilitate the maturation of autophagosomes in autophagy through interactions with Tom1 and autophagy receptors. Here authors report the structure of the cargobinding domain of Myosin VI in complex with Tom1, which provides insights into Myosin IV’s cargo recognition modes.
format article
author Shichen Hu
Yujiao Guo
Yingli Wang
Ying Li
Tao Fu
Zixuan Zhou
Yaru Wang
Jianping Liu
Lifeng Pan
author_facet Shichen Hu
Yujiao Guo
Yingli Wang
Ying Li
Tao Fu
Zixuan Zhou
Yaru Wang
Jianping Liu
Lifeng Pan
author_sort Shichen Hu
title Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering
title_short Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering
title_full Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering
title_fullStr Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering
title_full_unstemmed Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering
title_sort structure of myosin vi/tom1 complex reveals a cargo recognition mode of myosin vi for tethering
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/945bfe09b3fb4db79823e2b763ce2484
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AT jianpingliu structureofmyosinvitom1complexrevealsacargorecognitionmodeofmyosinvifortethering
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