Allelic variants of full-length VAR2CSA, the placental malaria vaccine candidate, differ in antigenicity and receptor binding affinity

Allelic variants of full-length VAR2CSA, the placental malaria vaccine candidate, differ in antigenicity and receptor binding affinity

Full-length VAR2CSA is a potential placental malaria vaccine candidate and in this study, Renn et al. compare antigenicity and receptor binding affinity of different allelic variants in blood samples from pregnant women. Their data show that inter-allelic differences may contribute to the heterogene...

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Autores principales: Jonathan P. Renn, Justin Y. A. Doritchamou, Bergeline C. Nguemwo Tentokam, Robert D. Morrison, Matthew V. Cowles, Martin Burkhardt, Rui Ma, Niraj H. Tolia, Michal Fried, Patrick E. Duffy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/9468370d9ab9416c980d5d735228618e
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