The quantitative comparison between high wall shear stress and high strain in the formation of paraclinoid aneurysms
Abstract In the hemodynamic study, computational fluid dynamics (CFD) analysis has shown that high wall shear stress (WSS) is an important parameter in cerebral aneurysm formation. However, CFD analysis is not more realistic than fluid–structure interaction (FSI) analysis given its lack of consideri...
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Nature Portfolio
2021
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oai:doaj.org-article:9468de7296e24d8d9f073d9c1bafbce72021-12-02T18:02:48ZThe quantitative comparison between high wall shear stress and high strain in the formation of paraclinoid aneurysms10.1038/s41598-021-87126-w2045-2322https://doaj.org/article/9468de7296e24d8d9f073d9c1bafbce72021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-87126-whttps://doaj.org/toc/2045-2322Abstract In the hemodynamic study, computational fluid dynamics (CFD) analysis has shown that high wall shear stress (WSS) is an important parameter in cerebral aneurysm formation. However, CFD analysis is not more realistic than fluid–structure interaction (FSI) analysis given its lack of considering the involvement of vascular structures. To investigate the relationship between the hemodynamic parameters and the aneurysm formation, the locations of high WSS and high strain were extracted from the CFD and FSI analyses, respectively. Then the distances between the aneurysm formation site and the locations of high WSS or high strain were calculated. A total of 37 intracranial paraclinoid aneurysms were enrolled for quantitative comparison. Additionally, the dura mater was modeled to facilitate realistic results in FSI analysis. The average distance from the location of the aneurysm formation site to the high strain (1.74 mm $$\pm $$ ± 1.04 mm) was smaller than the average distance to the high WSS (3.33 mm $$\pm $$ ± 1.18 mm). The presence of dura mater also influenced the findings in the aneurysm formation site. High strain extracted by FSI analysis is an important hemodynamic factor related to the formation of cerebral aneurysms. Strain parameter could help to predict the formation of aneurysms and elucidate the appropriate treatment.Jung-Jae KimHyeondong YangYong Bae KimJe Hoon OhKwang-Chun ChoNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021) |
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Medicine R Science Q Jung-Jae Kim Hyeondong Yang Yong Bae Kim Je Hoon Oh Kwang-Chun Cho The quantitative comparison between high wall shear stress and high strain in the formation of paraclinoid aneurysms |
| description |
Abstract In the hemodynamic study, computational fluid dynamics (CFD) analysis has shown that high wall shear stress (WSS) is an important parameter in cerebral aneurysm formation. However, CFD analysis is not more realistic than fluid–structure interaction (FSI) analysis given its lack of considering the involvement of vascular structures. To investigate the relationship between the hemodynamic parameters and the aneurysm formation, the locations of high WSS and high strain were extracted from the CFD and FSI analyses, respectively. Then the distances between the aneurysm formation site and the locations of high WSS or high strain were calculated. A total of 37 intracranial paraclinoid aneurysms were enrolled for quantitative comparison. Additionally, the dura mater was modeled to facilitate realistic results in FSI analysis. The average distance from the location of the aneurysm formation site to the high strain (1.74 mm $$\pm $$ ± 1.04 mm) was smaller than the average distance to the high WSS (3.33 mm $$\pm $$ ± 1.18 mm). The presence of dura mater also influenced the findings in the aneurysm formation site. High strain extracted by FSI analysis is an important hemodynamic factor related to the formation of cerebral aneurysms. Strain parameter could help to predict the formation of aneurysms and elucidate the appropriate treatment. |
| format |
article |
| author |
Jung-Jae Kim Hyeondong Yang Yong Bae Kim Je Hoon Oh Kwang-Chun Cho |
| author_facet |
Jung-Jae Kim Hyeondong Yang Yong Bae Kim Je Hoon Oh Kwang-Chun Cho |
| author_sort |
Jung-Jae Kim |
| title |
The quantitative comparison between high wall shear stress and high strain in the formation of paraclinoid aneurysms |
| title_short |
The quantitative comparison between high wall shear stress and high strain in the formation of paraclinoid aneurysms |
| title_full |
The quantitative comparison between high wall shear stress and high strain in the formation of paraclinoid aneurysms |
| title_fullStr |
The quantitative comparison between high wall shear stress and high strain in the formation of paraclinoid aneurysms |
| title_full_unstemmed |
The quantitative comparison between high wall shear stress and high strain in the formation of paraclinoid aneurysms |
| title_sort |
quantitative comparison between high wall shear stress and high strain in the formation of paraclinoid aneurysms |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/9468de7296e24d8d9f073d9c1bafbce7 |
| work_keys_str_mv |
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