Engineering Acetyl Coenzyme A Supply: Functional Expression of a Bacterial Pyruvate Dehydrogenase Complex in the Cytosol of <named-content content-type="genus-species">Saccharomyces cerevisiae</named-content>
ABSTRACT The energetic (ATP) cost of biochemical pathways critically determines the maximum yield of metabolites of vital or commercial relevance. Cytosolic acetyl coenzyme A (acetyl-CoA) is a key precursor for biosynthesis in eukaryotes and for many industrially relevant product pathways that have...
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Autores principales: | Barbara U. Kozak, Harmen M. van Rossum, Marijke A. H. Luttik, Michiel Akeroyd, Kirsten R. Benjamin, Liang Wu, Simon de Vries, Jean-Marc Daran, Jack T. Pronk, Antonius J. A. van Maris |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/946bda757b034a43b8cc702e6477923b |
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