Protein kinase A modulation of CaV1.4 calcium channels

Phosphorylation of L-type calcium CaV channels by protein kinase A is essential for several physiological events. Here, the authors show how this kinase regulates CaV1.4 activity, suggesting a general regulatory mechanism for all L-type calcium channels.

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Autores principales: Lingjie Sang, Ivy E. Dick, David T. Yue
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/946e436012b54cc6a4181a4bbcf12a18
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spelling oai:doaj.org-article:946e436012b54cc6a4181a4bbcf12a182021-12-02T14:39:52ZProtein kinase A modulation of CaV1.4 calcium channels10.1038/ncomms122392041-1723https://doaj.org/article/946e436012b54cc6a4181a4bbcf12a182016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12239https://doaj.org/toc/2041-1723Phosphorylation of L-type calcium CaV channels by protein kinase A is essential for several physiological events. Here, the authors show how this kinase regulates CaV1.4 activity, suggesting a general regulatory mechanism for all L-type calcium channels.Lingjie SangIvy E. DickDavid T. YueNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lingjie Sang
Ivy E. Dick
David T. Yue
Protein kinase A modulation of CaV1.4 calcium channels
description Phosphorylation of L-type calcium CaV channels by protein kinase A is essential for several physiological events. Here, the authors show how this kinase regulates CaV1.4 activity, suggesting a general regulatory mechanism for all L-type calcium channels.
format article
author Lingjie Sang
Ivy E. Dick
David T. Yue
author_facet Lingjie Sang
Ivy E. Dick
David T. Yue
author_sort Lingjie Sang
title Protein kinase A modulation of CaV1.4 calcium channels
title_short Protein kinase A modulation of CaV1.4 calcium channels
title_full Protein kinase A modulation of CaV1.4 calcium channels
title_fullStr Protein kinase A modulation of CaV1.4 calcium channels
title_full_unstemmed Protein kinase A modulation of CaV1.4 calcium channels
title_sort protein kinase a modulation of cav1.4 calcium channels
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/946e436012b54cc6a4181a4bbcf12a18
work_keys_str_mv AT lingjiesang proteinkinaseamodulationofcav14calciumchannels
AT ivyedick proteinkinaseamodulationofcav14calciumchannels
AT davidtyue proteinkinaseamodulationofcav14calciumchannels
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