Case of acute optic nerve compression caused by tuberculum sellae meningioma with optic canal involvement

Yuzhu Chai1, Hiroko Yamazaki1, Akihide Kondo2, Toshiyuki Oshitari3, Shuichi Yamamoto31Department of Ophthalmology, Kohnodai Hospital, National Center for Global Health and Medicine, Chiba, 2Department of Neurosurgery, Juntendo University, School of Medicine, Tokyo, 3Department of Ophtha...

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Autores principales: Chai Y, Yamazaki H, Kondo A, Oshitari T, Yamamoto S
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Publicado: Dove Medical Press 2012
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spelling oai:doaj.org-article:9477bcef627e4e65a55ac7706ebcd6eb2021-12-02T00:26:17ZCase of acute optic nerve compression caused by tuberculum sellae meningioma with optic canal involvement1177-54671177-5483https://doaj.org/article/9477bcef627e4e65a55ac7706ebcd6eb2012-05-01T00:00:00Zhttp://www.dovepress.com/case-of-acute-optic-nerve-compression-caused-by-tuberculum-sellae-meni-a9847https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Yuzhu Chai1, Hiroko Yamazaki1, Akihide Kondo2, Toshiyuki Oshitari3, Shuichi Yamamoto31Department of Ophthalmology, Kohnodai Hospital, National Center for Global Health and Medicine, Chiba, 2Department of Neurosurgery, Juntendo University, School of Medicine, Tokyo, 3Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, JapanAbstract: We present detailed ophthalmic findings in a case of tuberculum sellae meningioma with acute visual symptoms due to optic canal involvement. A 62-year-old Japanese woman reported a 1-week history of headaches and blurred vision in her left eye. Her visual acuity was 0.3 in the left eye with no ophthalmoscopic abnormalities. A relative afferent pupillary defect and inferior temporal field defect were found in the left eye. Pattern visual evoked potentials were undetectable in the left eye. Enhanced magnetic resonance imaging showed a 9 mm intracranial lesion around the left optic nerve anterior to the chiasm. She was diagnosed with granulomatous inflammation because of the increased cell counts and protein concentration in the cerebrospinal fluid. She was treated with steroid pulse therapy, and her visual acuity and visual field defect improved to normal in 3 weeks. However, 16 months after the onset, she suffered from headaches again and had a complete loss of vision in her left eye. There was no response to steroid pulse therapy. Enhanced magnetic resonance imaging revealed that the lesion had extended into the left optic canal, and emergency tumor removal surgery was carried out. The histopathological diagnosis was meningioma. One month after the surgery, her left visual acuity improved to 1.2, and her visual field was almost normal. Pattern visual evoked potentials were present but had a prolonged P100 latency of 170 ms. A thinning of the ganglion cell complex was detected by optical coherence tomography. Ophthalmologists should be aware that a small tuberculum sellae meningioma can cause acute visual symptoms due to optic canal involvement. Early consultation with a neurosurgeon is necessary. Visual evoked potentials and optical coherence tomography are sensitive and helpful in following patients with optic nerve compression.Keywords: optic nerve compression, tuberculum sellae meningioma, optic canal involvement, pattern visual evoked potentials, optical coherence tomographyChai YYamazaki HKondo AOshitari TYamamoto SDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 661-666 (2012)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Chai Y
Yamazaki H
Kondo A
Oshitari T
Yamamoto S
Case of acute optic nerve compression caused by tuberculum sellae meningioma with optic canal involvement
description Yuzhu Chai1, Hiroko Yamazaki1, Akihide Kondo2, Toshiyuki Oshitari3, Shuichi Yamamoto31Department of Ophthalmology, Kohnodai Hospital, National Center for Global Health and Medicine, Chiba, 2Department of Neurosurgery, Juntendo University, School of Medicine, Tokyo, 3Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, JapanAbstract: We present detailed ophthalmic findings in a case of tuberculum sellae meningioma with acute visual symptoms due to optic canal involvement. A 62-year-old Japanese woman reported a 1-week history of headaches and blurred vision in her left eye. Her visual acuity was 0.3 in the left eye with no ophthalmoscopic abnormalities. A relative afferent pupillary defect and inferior temporal field defect were found in the left eye. Pattern visual evoked potentials were undetectable in the left eye. Enhanced magnetic resonance imaging showed a 9 mm intracranial lesion around the left optic nerve anterior to the chiasm. She was diagnosed with granulomatous inflammation because of the increased cell counts and protein concentration in the cerebrospinal fluid. She was treated with steroid pulse therapy, and her visual acuity and visual field defect improved to normal in 3 weeks. However, 16 months after the onset, she suffered from headaches again and had a complete loss of vision in her left eye. There was no response to steroid pulse therapy. Enhanced magnetic resonance imaging revealed that the lesion had extended into the left optic canal, and emergency tumor removal surgery was carried out. The histopathological diagnosis was meningioma. One month after the surgery, her left visual acuity improved to 1.2, and her visual field was almost normal. Pattern visual evoked potentials were present but had a prolonged P100 latency of 170 ms. A thinning of the ganglion cell complex was detected by optical coherence tomography. Ophthalmologists should be aware that a small tuberculum sellae meningioma can cause acute visual symptoms due to optic canal involvement. Early consultation with a neurosurgeon is necessary. Visual evoked potentials and optical coherence tomography are sensitive and helpful in following patients with optic nerve compression.Keywords: optic nerve compression, tuberculum sellae meningioma, optic canal involvement, pattern visual evoked potentials, optical coherence tomography
format article
author Chai Y
Yamazaki H
Kondo A
Oshitari T
Yamamoto S
author_facet Chai Y
Yamazaki H
Kondo A
Oshitari T
Yamamoto S
author_sort Chai Y
title Case of acute optic nerve compression caused by tuberculum sellae meningioma with optic canal involvement
title_short Case of acute optic nerve compression caused by tuberculum sellae meningioma with optic canal involvement
title_full Case of acute optic nerve compression caused by tuberculum sellae meningioma with optic canal involvement
title_fullStr Case of acute optic nerve compression caused by tuberculum sellae meningioma with optic canal involvement
title_full_unstemmed Case of acute optic nerve compression caused by tuberculum sellae meningioma with optic canal involvement
title_sort case of acute optic nerve compression caused by tuberculum sellae meningioma with optic canal involvement
publisher Dove Medical Press
publishDate 2012
url https://doaj.org/article/9477bcef627e4e65a55ac7706ebcd6eb
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