Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore

Engineered biological nanopores enable observation of single molecule chemistry events; however a cylindrical pore geometry can have undesired effects. The authors report a conical biological pore which was embedded with tetrachloroaurate(III) to allow for discrimination between different biothiols.

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Autores principales:	Jiao Cao, Wendong Jia, Jinyue Zhang, Xiumei Xu, Shuanghong Yan, Yuqin Wang, Panke Zhang, Hong-Yuan Chen, Shuo Huang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/94823f338928445084725edff4f78e3a
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spelling	oai:doaj.org-article:94823f338928445084725edff4f78e3a2021-12-02T16:57:31ZGiant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore10.1038/s41467-019-13677-22041-1723https://doaj.org/article/94823f338928445084725edff4f78e3a2019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13677-2https://doaj.org/toc/2041-1723Engineered biological nanopores enable observation of single molecule chemistry events; however a cylindrical pore geometry can have undesired effects. The authors report a conical biological pore which was embedded with tetrachloroaurate(III) to allow for discrimination between different biothiols.Jiao CaoWendong JiaJinyue ZhangXiumei XuShuanghong YanYuqin WangPanke ZhangHong-Yuan ChenShuo HuangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jiao Cao Wendong Jia Jinyue Zhang Xiumei Xu Shuanghong Yan Yuqin Wang Panke Zhang Hong-Yuan Chen Shuo Huang Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore
description	Engineered biological nanopores enable observation of single molecule chemistry events; however a cylindrical pore geometry can have undesired effects. The authors report a conical biological pore which was embedded with tetrachloroaurate(III) to allow for discrimination between different biothiols.
format	article
author	Jiao Cao Wendong Jia Jinyue Zhang Xiumei Xu Shuanghong Yan Yuqin Wang Panke Zhang Hong-Yuan Chen Shuo Huang
author_facet	Jiao Cao Wendong Jia Jinyue Zhang Xiumei Xu Shuanghong Yan Yuqin Wang Panke Zhang Hong-Yuan Chen Shuo Huang
author_sort	Jiao Cao
title	Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore
title_short	Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore
title_full	Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore
title_fullStr	Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore
title_full_unstemmed	Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore
title_sort	giant single molecule chemistry events observed from a tetrachloroaurate(iii) embedded mycobacterium smegmatis porin a nanopore
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/94823f338928445084725edff4f78e3a
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Giant single molecule chemistry events observed from a tetrachloroaurate(III) embedded Mycobacterium smegmatis porin A nanopore

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