The concomitant estrogen-dependent diseases and the ovarian reserve condition for patients with severe peritoneal endometriosis, included in the vitro fertilization programmes

Aim. Is specification of the nature and frequency of concomitant forms of genital endometriosis and other estrogen-dependent diseases (EDD) for the infertile women with severe peritoneal endometriosis (PE), as well as the assessment of the ovarian reserve condition for the patients of different ages...

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Autores principales:	Irina Yu. Ershova, Ksenia V. Krasnopolskaya, Mekan R. Orazov, Elena V. Lagutina
Formato:	article
Lenguaje:	RU
Publicado:	IP Berlin A.V. 2021
Materias:	infertility peritoneal endometriosis ovarian reserve Gynecology and obstetrics RG1-991
Acceso en línea:	https://doaj.org/article/94a7baedbf244794b4cbb25f3afb4794
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spelling	oai:doaj.org-article:94a7baedbf244794b4cbb25f3afb47942021-12-02T19:22:24ZThe concomitant estrogen-dependent diseases and the ovarian reserve condition for patients with severe peritoneal endometriosis, included in the vitro fertilization programmes2079-56962079-583110.26442/20795696.2021.5.201058https://doaj.org/article/94a7baedbf244794b4cbb25f3afb47942021-11-01T00:00:00Zhttps://gynecology.orscience.ru/2079-5831/article/viewFile/88599/66779https://doaj.org/toc/2079-5696https://doaj.org/toc/2079-5831Aim. Is specification of the nature and frequency of concomitant forms of genital endometriosis and other estrogen-dependent diseases (EDD) for the infertile women with severe peritoneal endometriosis (PE), as well as the assessment of the ovarian reserve condition for the patients of different ages. Materials and methods. The total 142 infertile women with severe peritoneal endometriosis (IIIIV stage of the external genital endometriosis according to the American Fertility Society classification) were examined at the age of 32.33.2 years (minmax = 2340 years). The clinical status assessment was conducted, using a standard set of diagnostic procedures, prescribed for the inclusion of patients in the IVF program. The ovarian reserve was estimated by the level of the anti-Mullerian Hormone level determined by the immunoenzyme method. Results. The concomitant 2-sided endometriotic ovarian cysts (96%), myoma (19.7%) and the adenomyosis (16.9%) were most common for the patients with severe peritoneal endometriosis. The severely reduced the anti-Mullerian Hormone rates (0.4 ng/ml) were much higher among patients 35 years old (24.6% compared to 10.6% for younger patients; p=0.028). Conclusion. The infertility for severe peritoneal endometriosis is supported by concomitant estrogen-dependent diseases, of which 2-sided endometriomas, adenomyosis and uterine myoma are of the most pathological. The low efficiency of IVF in the treatment of patients with severe peritoneal endometriosis and concomitant estrogen-dependent diseases is explained by the aggravation of the embryonic and endometrial factors for the infertility. The other reason that worsens the results of IVF for such patients is late reproductive age (35 years) that increases the observed reduction of the ovarian reserve.Irina Yu. ErshovaKsenia V. KrasnopolskayaMekan R. OrazovElena V. LagutinaIP Berlin A.V. articleinfertilityperitoneal endometriosisovarian reserveGynecology and obstetricsRG1-991RUГинекология, Vol 23, Iss 5, Pp 386-391 (2021)
institution	DOAJ
collection	DOAJ
language	RU
topic	infertility peritoneal endometriosis ovarian reserve Gynecology and obstetrics RG1-991
spellingShingle	infertility peritoneal endometriosis ovarian reserve Gynecology and obstetrics RG1-991 Irina Yu. Ershova Ksenia V. Krasnopolskaya Mekan R. Orazov Elena V. Lagutina The concomitant estrogen-dependent diseases and the ovarian reserve condition for patients with severe peritoneal endometriosis, included in the vitro fertilization programmes
description	Aim. Is specification of the nature and frequency of concomitant forms of genital endometriosis and other estrogen-dependent diseases (EDD) for the infertile women with severe peritoneal endometriosis (PE), as well as the assessment of the ovarian reserve condition for the patients of different ages. Materials and methods. The total 142 infertile women with severe peritoneal endometriosis (IIIIV stage of the external genital endometriosis according to the American Fertility Society classification) were examined at the age of 32.33.2 years (minmax = 2340 years). The clinical status assessment was conducted, using a standard set of diagnostic procedures, prescribed for the inclusion of patients in the IVF program. The ovarian reserve was estimated by the level of the anti-Mullerian Hormone level determined by the immunoenzyme method. Results. The concomitant 2-sided endometriotic ovarian cysts (96%), myoma (19.7%) and the adenomyosis (16.9%) were most common for the patients with severe peritoneal endometriosis. The severely reduced the anti-Mullerian Hormone rates (0.4 ng/ml) were much higher among patients 35 years old (24.6% compared to 10.6% for younger patients; p=0.028). Conclusion. The infertility for severe peritoneal endometriosis is supported by concomitant estrogen-dependent diseases, of which 2-sided endometriomas, adenomyosis and uterine myoma are of the most pathological. The low efficiency of IVF in the treatment of patients with severe peritoneal endometriosis and concomitant estrogen-dependent diseases is explained by the aggravation of the embryonic and endometrial factors for the infertility. The other reason that worsens the results of IVF for such patients is late reproductive age (35 years) that increases the observed reduction of the ovarian reserve.
format	article
author	Irina Yu. Ershova Ksenia V. Krasnopolskaya Mekan R. Orazov Elena V. Lagutina
author_facet	Irina Yu. Ershova Ksenia V. Krasnopolskaya Mekan R. Orazov Elena V. Lagutina
author_sort	Irina Yu. Ershova
title	The concomitant estrogen-dependent diseases and the ovarian reserve condition for patients with severe peritoneal endometriosis, included in the vitro fertilization programmes
title_short	The concomitant estrogen-dependent diseases and the ovarian reserve condition for patients with severe peritoneal endometriosis, included in the vitro fertilization programmes
title_full	The concomitant estrogen-dependent diseases and the ovarian reserve condition for patients with severe peritoneal endometriosis, included in the vitro fertilization programmes
title_fullStr	The concomitant estrogen-dependent diseases and the ovarian reserve condition for patients with severe peritoneal endometriosis, included in the vitro fertilization programmes
title_full_unstemmed	The concomitant estrogen-dependent diseases and the ovarian reserve condition for patients with severe peritoneal endometriosis, included in the vitro fertilization programmes
title_sort	concomitant estrogen-dependent diseases and the ovarian reserve condition for patients with severe peritoneal endometriosis, included in the vitro fertilization programmes
publisher	IP Berlin A.V.
publishDate	2021
url	https://doaj.org/article/94a7baedbf244794b4cbb25f3afb4794
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The concomitant estrogen-dependent diseases and the ovarian reserve condition for patients with severe peritoneal endometriosis, included in the vitro fertilization programmes

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