Heart enhancers with deeply conserved regulatory activity are established early in zebrafish development

During early embryogenesis, critical cardiac specification events occur. Here the authors isolate cardiac progenitor cells from early zebrafish embryos and characterize accessible chromatin regions specific to this cell population, finding that many of these regions overlap with conserved non-coding...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Xuefei Yuan, Mengyi Song, Patrick Devine, Benoit G. Bruneau, Ian C. Scott, Michael D. Wilson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/94a903ccf4c5448d82b763ec343416b4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:94a903ccf4c5448d82b763ec343416b4
record_format	dspace
spelling	oai:doaj.org-article:94a903ccf4c5448d82b763ec343416b42021-12-02T14:39:25ZHeart enhancers with deeply conserved regulatory activity are established early in zebrafish development10.1038/s41467-018-07451-z2041-1723https://doaj.org/article/94a903ccf4c5448d82b763ec343416b42018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07451-zhttps://doaj.org/toc/2041-1723During early embryogenesis, critical cardiac specification events occur. Here the authors isolate cardiac progenitor cells from early zebrafish embryos and characterize accessible chromatin regions specific to this cell population, finding that many of these regions overlap with conserved non-coding elements that are ortholgous to accessible chromatin regions in human.Xuefei YuanMengyi SongPatrick DevineBenoit G. BruneauIan C. ScottMichael D. WilsonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xuefei Yuan Mengyi Song Patrick Devine Benoit G. Bruneau Ian C. Scott Michael D. Wilson Heart enhancers with deeply conserved regulatory activity are established early in zebrafish development
description	During early embryogenesis, critical cardiac specification events occur. Here the authors isolate cardiac progenitor cells from early zebrafish embryos and characterize accessible chromatin regions specific to this cell population, finding that many of these regions overlap with conserved non-coding elements that are ortholgous to accessible chromatin regions in human.
format	article
author	Xuefei Yuan Mengyi Song Patrick Devine Benoit G. Bruneau Ian C. Scott Michael D. Wilson
author_facet	Xuefei Yuan Mengyi Song Patrick Devine Benoit G. Bruneau Ian C. Scott Michael D. Wilson
author_sort	Xuefei Yuan
title	Heart enhancers with deeply conserved regulatory activity are established early in zebrafish development
title_short	Heart enhancers with deeply conserved regulatory activity are established early in zebrafish development
title_full	Heart enhancers with deeply conserved regulatory activity are established early in zebrafish development
title_fullStr	Heart enhancers with deeply conserved regulatory activity are established early in zebrafish development
title_full_unstemmed	Heart enhancers with deeply conserved regulatory activity are established early in zebrafish development
title_sort	heart enhancers with deeply conserved regulatory activity are established early in zebrafish development
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/94a903ccf4c5448d82b763ec343416b4
work_keys_str_mv	AT xuefeiyuan heartenhancerswithdeeplyconservedregulatoryactivityareestablishedearlyinzebrafishdevelopment AT mengyisong heartenhancerswithdeeplyconservedregulatoryactivityareestablishedearlyinzebrafishdevelopment AT patrickdevine heartenhancerswithdeeplyconservedregulatoryactivityareestablishedearlyinzebrafishdevelopment AT benoitgbruneau heartenhancerswithdeeplyconservedregulatoryactivityareestablishedearlyinzebrafishdevelopment AT iancscott heartenhancerswithdeeplyconservedregulatoryactivityareestablishedearlyinzebrafishdevelopment AT michaeldwilson heartenhancerswithdeeplyconservedregulatoryactivityareestablishedearlyinzebrafishdevelopment
_version_	1718390604972425216

Heart enhancers with deeply conserved regulatory activity are established early in zebrafish development

Ejemplares similares