A draft map of the mouse pluripotent stem cell spatial proteome
The spatial location of proteins within a cell is a key element of protein function. Here the authors describe hyperLOPIT—a proteomics workflow that allows the simultaneous assignment of thousands of proteins to subcellular niches with high resolution—and apply it to mouse pluripotent stem cells....
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Nature Portfolio
2016
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oai:doaj.org-article:94b699fb21c4417090182a6c8cb87d482021-12-02T16:57:04ZA draft map of the mouse pluripotent stem cell spatial proteome10.1038/ncomms99922041-1723https://doaj.org/article/94b699fb21c4417090182a6c8cb87d482016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms9992https://doaj.org/toc/2041-1723The spatial location of proteins within a cell is a key element of protein function. Here the authors describe hyperLOPIT—a proteomics workflow that allows the simultaneous assignment of thousands of proteins to subcellular niches with high resolution—and apply it to mouse pluripotent stem cells.Andy ChristoforouClaire M. MulveyLisa M. BreckelsAikaterini GeladakiTracey HurrellPenelope C. HaywardThomas NaakeLaurent GattoRosa VinerAlfonso Martinez AriasKathryn S. LilleyNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016) |
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Science Q Andy Christoforou Claire M. Mulvey Lisa M. Breckels Aikaterini Geladaki Tracey Hurrell Penelope C. Hayward Thomas Naake Laurent Gatto Rosa Viner Alfonso Martinez Arias Kathryn S. Lilley A draft map of the mouse pluripotent stem cell spatial proteome |
description |
The spatial location of proteins within a cell is a key element of protein function. Here the authors describe hyperLOPIT—a proteomics workflow that allows the simultaneous assignment of thousands of proteins to subcellular niches with high resolution—and apply it to mouse pluripotent stem cells. |
format |
article |
author |
Andy Christoforou Claire M. Mulvey Lisa M. Breckels Aikaterini Geladaki Tracey Hurrell Penelope C. Hayward Thomas Naake Laurent Gatto Rosa Viner Alfonso Martinez Arias Kathryn S. Lilley |
author_facet |
Andy Christoforou Claire M. Mulvey Lisa M. Breckels Aikaterini Geladaki Tracey Hurrell Penelope C. Hayward Thomas Naake Laurent Gatto Rosa Viner Alfonso Martinez Arias Kathryn S. Lilley |
author_sort |
Andy Christoforou |
title |
A draft map of the mouse pluripotent stem cell spatial proteome |
title_short |
A draft map of the mouse pluripotent stem cell spatial proteome |
title_full |
A draft map of the mouse pluripotent stem cell spatial proteome |
title_fullStr |
A draft map of the mouse pluripotent stem cell spatial proteome |
title_full_unstemmed |
A draft map of the mouse pluripotent stem cell spatial proteome |
title_sort |
draft map of the mouse pluripotent stem cell spatial proteome |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/94b699fb21c4417090182a6c8cb87d48 |
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