The transbasal approach to the anterior skull base: surgical outcome of a single-centre case series

Abstract A variety of sinonasal tumours, meningiomas or other lesions of the anterior skull base involve the paranasal sinuses and the periorbital area. The transbasal approach (TBA) has turned out to be a feasible technique to reach those lesions. A retrospective review at a neurosurgical universit...

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Autores principales:	A. Kaywan Aftahy, Melanie Barz, Arthur Wagner, Julia S. Bermeitinger, Claire Delbridge, Chiara Negwer, Bernhard Meyer, Jens Gempt
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/94c74ca4c1a74fd3b09052a0760536d5
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spelling	oai:doaj.org-article:94c74ca4c1a74fd3b09052a0760536d52021-12-02T15:12:41ZThe transbasal approach to the anterior skull base: surgical outcome of a single-centre case series10.1038/s41598-020-80255-82045-2322https://doaj.org/article/94c74ca4c1a74fd3b09052a0760536d52020-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-80255-8https://doaj.org/toc/2045-2322Abstract A variety of sinonasal tumours, meningiomas or other lesions of the anterior skull base involve the paranasal sinuses and the periorbital area. The transbasal approach (TBA) has turned out to be a feasible technique to reach those lesions. A retrospective review at a neurosurgical university department between November 2007 and January 2020 with adult patients who underwent resection of oncologic pathologies through TBA. Surgical technique, extent of resection (EOR), clinical outcome and postoperative complications were analysed. 18 TBAs between November 2007 and January 2020 were performed. Median age was 62 (range 25–83), 7 female and 11 male patients. Gross total resection rate was 85.8% throughout all entities. Four (22.2%) patients suffered from WHO°I meningiomas and 14 (77.7%) from other extra-axial lesions. Preoperative Karnofsky Performance Status Scale (KPSS) was 80% (range 40–90), postoperative KPSS 80% (range 20–100). Rate of postoperative complications requiring intervention was 16.7%. Median follow-up was 9.8 (range 1.2–71.8) months. Modifications and extensions of the classic TBA are not mandatory. Complete resection can be performed under functional and cosmetic-preserving aspects. Second-step procedures such as transnasal approaches may be performed to avoid high morbidity of more aggressive TBAs, if necessary. Surgical considerations should be kept simple and straightforward.A. Kaywan AftahyMelanie BarzArthur WagnerJulia S. BermeitingerClaire DelbridgeChiara NegwerBernhard MeyerJens GemptNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q A. Kaywan Aftahy Melanie Barz Arthur Wagner Julia S. Bermeitinger Claire Delbridge Chiara Negwer Bernhard Meyer Jens Gempt The transbasal approach to the anterior skull base: surgical outcome of a single-centre case series
description	Abstract A variety of sinonasal tumours, meningiomas or other lesions of the anterior skull base involve the paranasal sinuses and the periorbital area. The transbasal approach (TBA) has turned out to be a feasible technique to reach those lesions. A retrospective review at a neurosurgical university department between November 2007 and January 2020 with adult patients who underwent resection of oncologic pathologies through TBA. Surgical technique, extent of resection (EOR), clinical outcome and postoperative complications were analysed. 18 TBAs between November 2007 and January 2020 were performed. Median age was 62 (range 25–83), 7 female and 11 male patients. Gross total resection rate was 85.8% throughout all entities. Four (22.2%) patients suffered from WHO°I meningiomas and 14 (77.7%) from other extra-axial lesions. Preoperative Karnofsky Performance Status Scale (KPSS) was 80% (range 40–90), postoperative KPSS 80% (range 20–100). Rate of postoperative complications requiring intervention was 16.7%. Median follow-up was 9.8 (range 1.2–71.8) months. Modifications and extensions of the classic TBA are not mandatory. Complete resection can be performed under functional and cosmetic-preserving aspects. Second-step procedures such as transnasal approaches may be performed to avoid high morbidity of more aggressive TBAs, if necessary. Surgical considerations should be kept simple and straightforward.
format	article
author	A. Kaywan Aftahy Melanie Barz Arthur Wagner Julia S. Bermeitinger Claire Delbridge Chiara Negwer Bernhard Meyer Jens Gempt
author_facet	A. Kaywan Aftahy Melanie Barz Arthur Wagner Julia S. Bermeitinger Claire Delbridge Chiara Negwer Bernhard Meyer Jens Gempt
author_sort	A. Kaywan Aftahy
title	The transbasal approach to the anterior skull base: surgical outcome of a single-centre case series
title_short	The transbasal approach to the anterior skull base: surgical outcome of a single-centre case series
title_full	The transbasal approach to the anterior skull base: surgical outcome of a single-centre case series
title_fullStr	The transbasal approach to the anterior skull base: surgical outcome of a single-centre case series
title_full_unstemmed	The transbasal approach to the anterior skull base: surgical outcome of a single-centre case series
title_sort	transbasal approach to the anterior skull base: surgical outcome of a single-centre case series
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/94c74ca4c1a74fd3b09052a0760536d5
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The transbasal approach to the anterior skull base: surgical outcome of a single-centre case series

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