Unraveling the binding characteristics of small ligands to telomeric DNA by pressure modulation

Abstract Recently, non-canonical DNA structures, such as G-quadruplexes (GQs), were found to be highly pressure sensitive, suggesting that pressure modulation studies can provide additional mechanistic details of such biomolecular systems. Using FRET and CD spectroscopy as well as binding equilibriu...

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Autores principales: Rosario Oliva, Sanjib Mukherjee, Roland Winter
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/94c9a90a87ed4256a5459e738bc7c9de
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